Development Level

Tbio 44 | 11,651
Tclin 19 | 612
Tchem 14 | 1,388
Tdark 3 | 6,593

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 6 | 499
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased circulating sodium l... 3 | 71
abnormal embryo size 2 | 220
enlarged heart 2 | 210
increased circulating glucose ... 2 | 24
increased heart weight 2 | 62
male infertility 2 | 123
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal embryo turning 1 | 31
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal outer ear morphology 1 | 3
abnormal rib morphology 1 | 10
cataract 1 | 92
cyanosis 1 | 7
decreased NK T cell number 1 | 2
decreased circulating creatine... 1 | 4
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged uterus 1 | 11
hemorrhage 1 | 23
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased circulating chloride... 1 | 41
increased circulating creatine... 1 | 5
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
prenatal lethality 1 | 28
sclerocornea 1 | 2
short tibia 1 | 97
shortened RR interval 1 | 17
small heart 1 | 10
small kidney 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Neuroblastoma 80 | 80
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 76 | 18,159
Digestive Tract 74 | 17,369
Female tissues 73 | 17,400
Skin and soft tissues 73 | 17,230
Blood and immune system 72 | 16,909
Male tissues 72 | 17,142
Nervous System 72 | 16,725
Liver and Pancreas 70 | 16,750
Urinary Tract 70 | 16,678
Respiratory system 68 | 16,393
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 37 | 12,091
Enzyme 19 | 4,145
Kinase 9 | 634
Transcription Factor 8 | 1,400
Epigenetic 3 | 242
Transporter 2 | 473
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 2 subunit alpha SCN2A Tclin Ion Channel -3.11580 1268.8 107
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Tubulin beta-3 chain TUBB3 Tclin Non-IDG -2.08746 87.9 594
Tubulin beta-2B chain TUBB2B Tclin Non-IDG -1.23205 14.6 234
E3 ubiquitin-protein ligase RNF26 RNF26 Tbio Non-IDG -0.14435 1.94 81
Serine/threonine-protein kinase PINK1, mitochondrial PINK1 Tbio Kinase -2.81574 706.5 546
Hepatocyte growth factor HGF Tchem Enzyme -3.30841 2392.1 724
Tubulin beta-2A chain TUBB2A Tclin Non-IDG -1.63227 39.0 257
Tumor necrosis factor ligand superfamily member 10 TNFSF10 Tbio Non-IDG -2.87006 661.9 949
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.28550 20244.6 3859