Development Level

Tclin 14 | 613
Tbio 4 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal male genitalia morpho... 1 | 3
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating phosphat... 1 | 27
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
increased total body fat amoun... 1 | 134
oligodactyly 1 | 1
polydactyly 1 | 7
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small kidney 1 | 16

Disease

Neuralgia 20 | 20
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Skin and soft tissues 18 | 17,230
Blood and immune system 17 | 16,909
Digestive Tract 17 | 17,369
Nervous System 17 | 16,725
Urinary Tract 17 | 16,678
Respiratory system 16 | 16,393
Cardiovascular System 12 | 15,192

Target Family

Ion Channel 8 | 344
Non-IDG 5 | 12,091
GPCR 4 | 408
Enzyme 1 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Sodium channel protein type 3 subunit alpha SCN3A Tclin Ion Channel -1.98160 87.0 76
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369
Transient receptor potential cation channel subfamily V member 1 TRPV1 Tclin Ion Channel -3.26780 1774.6 373
Sodium channel protein type 4 subunit alpha SCN4A Tclin Ion Channel -2.57811 366.4 57
Advanced glycosylation end product-specific receptor AGER Tchem Non-IDG -2.29145 187.3 589
Sodium channel protein type 9 subunit alpha SCN9A Tclin Ion Channel -2.57994 379.2 327
5-hydroxytryptamine receptor 2C HTR2C Tclin GPCR -3.08158 1199.3 336