Development Level

Tbio 19 | 10,625
Tchem 11 | 1,890
Tclin 1 | 602

IMPC Phenotype

preweaning lethality, complete... 3 | 633
abnormal embryo size 2 | 112
abnormal eye morphology 2 | 38
abnormal hindbrain development 2 | 24
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
abnormal placenta size 2 | 10
abnormal retina morphology 2 | 100
craniofacial phenotype 2 | 9
short snout 2 | 4
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal forebrain development 1 | 18
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal pericardium morpholog... 1 | 11
abnormal respiratory quotient 1 | 9
abnormal retinal pigmentation 1 | 61
abnormal spinal cord morpholog... 1 | 8
abnormal startle reflex 1 | 14
curly tail 1 | 1
decreased IgE level 1 | 3
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating triglyce... 1 | 83
decreased fasted circulating g... 1 | 49
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
enlarged heart atrium 1 | 2
enlarged lymph nodes 1 | 27
herniated abdominal wall 1 | 4
impaired glucose tolerance 1 | 52
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased circulating calcium ... 1 | 32
increased circulating creatini... 1 | 29
increased circulating glucose ... 1 | 16
increased exploration in new e... 1 | 56
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased or absent threshold ... 1 | 128
kinked tail 1 | 3
pale yolk sac 1 | 12
prenatal lethality prior to he... 1 | 64
shortened head 1 | 2

Disease

Neural Tube Defects 31 | 31
ovarian cancer 8,491 | 8,491
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,098 | 3,098
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,170 | 1,170
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 966 | 966
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 788 | 788
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 764 | 764
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 334 | 334
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Blood and immune system 31 | 17,994
Cardiovascular System 31 | 17,957
Digestive Tract 31 | 18,472
Endocrine System 31 | 18,511
Female tissues 31 | 18,646
Liver and Pancreas 31 | 18,135
Nervous System 31 | 18,560
Skin and soft tissues 31 | 18,114
Urinary Tract 31 | 18,443
Male tissues 30 | 17,968
Respiratory system 30 | 17,483

Target Family

Non-IDG 15 | 11,969
Enzyme 7 | 4,146
Transcription Factor 6 | 1,400
GPCR 2 | 408
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
Vang-like protein 2 VANGL2 Tbio Non-IDG -2.26133 182.3 138
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.16064 142.8 42
Folate receptor beta FOLR2 Tchem Non-IDG -1.86286 82.1 165
Dapper homolog 1 DACT1 Tbio Non-IDG -1.84982 75.1 93
Zinc finger protein ZIC 5 ZIC5 Tbio Transcription Factor -0.91124 7.71 71
Cadherin EGF LAG seven-pass G-type receptor 1 CELSR1 Tbio GPCR -1.44011 31.7 110
Kunitz-type protease inhibitor 2 SPINT2 Tbio Enzyme -2.21043 163.8 236
Cytochrome P450 1A2 CYP1A2 Tchem Non-IDG -3.31421 2022.5 420
Zinc finger protein ZIC 2 ZIC2 Tbio Transcription Factor -1.85073 74.2 141