Development Level

Tbio 55 | 11,651
Tdark 23 | 6,593
Tchem 2 | 1,388

Collection

Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 14 | 979
abnormal embryo size 3 | 220
embryonic lethality prior to t... 3 | 278
abnormal behavior 2 | 298
decreased body weight 2 | 161
edema 2 | 59
embryonic growth retardation 2 | 106
hydrometra 2 | 53
increased blood urea nitrogen ... 2 | 48
small superior vagus ganglion 2 | 74
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal forebrain morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal midbrain morphology 1 | 10
abnormal nail morphology 1 | 8
abnormal neural tube closure 1 | 46
abnormal pericardium morpholog... 1 | 26
abnormal response to tactile s... 1 | 17
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
cataract 1 | 92
decreased circulating triglyce... 1 | 79
decreased food intake 1 | 13
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
enlarged heart 1 | 210
enlarged uterus 1 | 11
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
long tibia 1 | 25
male infertility 1 | 123
microphthalmia 1 | 26
polydactyly 1 | 7
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Nephronophthisis 80 | 80
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 80 | 17,369
Endocrine System 80 | 18,159
Skin and soft tissues 80 | 17,230
Liver and Pancreas 79 | 16,750
Male tissues 79 | 17,142
Urinary Tract 79 | 16,678
Nervous System 78 | 16,725
Female tissues 77 | 17,400
Blood and immune system 76 | 16,909
Respiratory system 76 | 16,393
Cardiovascular System 71 | 15,192

Target Family

Non-IDG 59 | 12,091
Enzyme 9 | 4,145
Transcription Factor 4 | 1,400
Transporter 4 | 473
Kinase 3 | 634
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
GREB1-like protein GREB1L Tbio Non-IDG -0.47366 3.53 6
Centrosomal protein of 83 kDa CEP83 Tdark Non-IDG -0.47180 2.89 0
DCC-interacting protein 13-alpha APPL1 Tbio Non-IDG -2.75344 511.0 230
Tubulointerstitial nephritis antigen TINAG Tbio Non-IDG -1.39157 27.8 58
Dynactin subunit 5 DCTN5 Tdark Non-IDG -0.32495 0.71 53
Protein jagged-1 JAG1 Tbio Non-IDG -3.09216 1190.8 473
Intraflagellar transport protein 122 homolog IFT122 Tbio Non-IDG -1.52417 33.7 53
Mucin-1 MUC1 Tbio Non-IDG -3.54835 3730.1 2598
Ankyrin repeat and MYND domain-containing protein 2 ANKMY2 Tdark Non-IDG 0.07 0.92 97