Development Level

Tbio 93 | 10,625
Tchem 56 | 1,890
Tclin 19 | 602
Tdark 1 | 7,003

IMPC Term

decreased total body fat amoun... 4 | 186
preweaning lethality, complete... 4 | 633
abnormal coat/hair pigmentatio... 3 | 54
increased bone mineral content 3 | 92
increased mean corpuscular vol... 3 | 91
abnormal behavior 2 | 226
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 77
decreased circulating triglyce... 2 | 83
decreased grip strength 2 | 123
decreased lean body mass 2 | 195
decreased prepulse inhibition 2 | 52
decreased startle reflex 2 | 48
increased circulating HDL chol... 2 | 63
increased lean body mass 2 | 107
increased mean corpuscular hem... 2 | 93
abnormal QRS complex 1 | 25
abnormal bone mineralization 1 | 55
abnormal coat/ hair morphology 1 | 18
abnormal ear morphology 1 | 5
abnormal eye morphology 1 | 38
abnormal foot plate morphology 1 | 2
abnormal gait 1 | 51
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 2
abnormal lens morphology 1 | 73
abnormal liver size 1 | 4
abnormal lung morphology 1 | 15
abnormal retina morphology 1 | 100
abnormal skin coloration 1 | 18
abnormal sleep behavior 1 | 63
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 2
absent startle reflex 1 | 15
cataract 1 | 26
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased circulating unsatura... 1 | 1
decreased fasted circulating g... 1 | 49
decreased food intake 1 | 6
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased red blood cell distr... 1 | 11
decreased thermal nociceptive ... 1 | 4
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
female infertility 1 | 34
hyperactivity 1 | 108
hypoactivity 1 | 89
increased bone mineral density 1 | 52
increased circulating choleste... 1 | 53
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased hemoglobin content 1 | 45
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
limb grasping 1 | 35
male infertility 1 | 62
oligodactyly 1 | 14
pale liver 1 | 5
pallor 1 | 13
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
prolonged PR interval 1 | 4
short tibia 1 | 82
small superior vagus ganglion 1 | 20
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

Myocardial Ischemia 169 | 169
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Blood and immune system 167 | 17,995
Cardiovascular System 167 | 17,958
Digestive Tract 167 | 18,473
Endocrine System 167 | 18,512
Female tissues 167 | 18,647
Liver and Pancreas 167 | 18,136
Male tissues 167 | 17,969
Nervous System 167 | 18,561
Urinary Tract 167 | 18,444
Respiratory system 166 | 17,484
Skin and soft tissues 166 | 18,115

Target Family

Non-IDG 87 | 11,971
Enzyme 43 | 4,146
Transcription Factor 15 | 1,400
Kinase 14 | 634
GPCR 3 | 406
Transporter 3 | 473
Ion Channel 2 | 341
Nuclear Receptor 2 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
mRNA decay activator protein ZFP36 ZFP36 Tbio Non-IDG -2.38153 220.3 0
Trifunctional enzyme subunit alpha, mitochondrial HADHA Tbio Non-IDG -2.96515 948.2 132
Glycine amidinotransferase, mitochondrial GATM Tbio Enzyme -2.31313 210.4 193
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.39868 2437.0 1167
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.60609 403.7 216
Complement C1q subcomponent subunit B C1QB Tbio Non-IDG -1.63026 41.3 161
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34160 1960.9 1181
G1/S-specific cyclin-D1 CCND1 Tchem Non-IDG -3.77851 5447.1 1111