Development Level

Tbio 415 | 11,445
Tchem 83 | 1,598
Tclin 65 | 613
Tdark 8 | 6,588

Collection

Ion Channel: IDG Consortium (T... 4 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 72 | 979
embryonic lethality prior to o... 18 | 239
embryonic lethality prior to t... 17 | 278
abnormal behavior 16 | 298
preweaning lethality, incomple... 15 | 499
decreased total body fat amoun... 12 | 207
hyperactivity 11 | 148
decreased body weight 10 | 161
abnormal embryo size 9 | 220
decreased bone mineral density 9 | 126
decreased grip strength 8 | 116
decreased vertical activity 8 | 208
enlarged heart 8 | 210
hypoactivity 8 | 132
male infertility 8 | 123
decreased circulating choleste... 7 | 93
decreased lean body mass 7 | 135
impaired glucose tolerance 7 | 75
increased bone mineral density 7 | 72
increased circulating alkaline... 7 | 122
increased mean corpuscular hem... 7 | 96
abnormal heart morphology 6 | 162
abnormal lens morphology 6 | 81
decreased mean corpuscular vol... 6 | 79
improved glucose tolerance 6 | 79
increased lean body mass 6 | 172
short tibia 6 | 97
abnormal gait 5 | 69
cataract 5 | 92
decreased body length 5 | 101
decreased bone mineral content 5 | 151
decreased circulating HDL chol... 5 | 68
decreased circulating glucose ... 5 | 126
decreased lymphocyte cell numb... 5 | 83
hydrometra 5 | 53
increased total body fat amoun... 5 | 134
small superior vagus ganglion 5 | 74
small testis 5 | 58
abnormal bone structure 4 | 187
abnormal coat-hair pigmentatio... 4 | 64
abnormal eye morphology 4 | 68
abnormal locomotor behavior 4 | 24
decreased circulating triglyce... 4 | 79
decreased erythrocyte cell num... 4 | 62
decreased leukocyte cell numbe... 4 | 73
decreased prepulse inhibition 4 | 82
decreased startle reflex 4 | 75
embryonic growth retardation 4 | 106
enlarged lymph nodes 4 | 37
increased bone mineral content 4 | 108
increased circulating phosphat... 4 | 26
increased monocyte cell number 4 | 63
increased startle reflex 4 | 112
abnormal bone mineralization 3 | 38
abnormal cornea morphology 3 | 31
abnormal kidney morphology 3 | 65
abnormal neural tube closure 3 | 46
abnormal retina morphology 3 | 71
abnormal tibia morphology 3 | 14
anophthalmia 3 | 33
decreased blood urea nitrogen ... 3 | 51
decreased caudal vertebrae num... 3 | 53
decreased circulating aspartat... 3 | 34
decreased circulating fructosa... 3 | 30
decreased circulating serum al... 3 | 82
decreased fasted circulating g... 3 | 65
decreased heart weight 3 | 27
decreased mean platelet volume 3 | 25
decreased red blood cell distr... 3 | 41
enlarged spleen 3 | 41
increased body length 3 | 32
increased body weight 3 | 25
increased circulating calcium ... 3 | 34
increased circulating sodium l... 3 | 71
increased fasted circulating g... 3 | 76
increased heart weight 3 | 62
increased mean corpuscular vol... 3 | 92
increased neutrophil cell numb... 3 | 46
limb grasping 3 | 41
microphthalmia 3 | 26
prenatal lethality prior to he... 3 | 87
small kidney 3 | 16
tremors 3 | 39
abnormal epididymis morphology 2 | 42
abnormal lung morphology 2 | 26
abnormal pancreas morphology 2 | 13
abnormal retinal vasculature m... 2 | 27
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
abnormal spleen morphology 2 | 55
abnormal vertebrae morphology 2 | 18
corneal opacity 2 | 32
decreased circulating calcium ... 2 | 36
decreased circulating insulin ... 2 | 76
decreased hemoglobin content 2 | 68
decreased pulmonary respirator... 2 | 5
increased circulating amylase ... 2 | 25
increased circulating bilirubi... 2 | 16
increased circulating chloride... 2 | 41
increased prepulse inhibition 2 | 32

Disease

Muscle hypotonia 571 | 571
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 567 | 18,159
Digestive Tract 561 | 17,369
Skin and soft tissues 560 | 17,230
Nervous System 558 | 16,725
Female tissues 556 | 17,400
Blood and immune system 555 | 16,909
Male tissues 555 | 17,142
Liver and Pancreas 553 | 16,750
Urinary Tract 546 | 16,678
Respiratory system 542 | 16,393
Cardiovascular System 525 | 15,192

Target Family

Enzyme 223 | 4,145
Non-IDG 207 | 12,091
Transcription Factor 47 | 1,400
Ion Channel 26 | 344
Kinase 24 | 634
Transporter 19 | 473
Epigenetic 16 | 242
GPCR 4 | 408
Nuclear Receptor 4 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Isobutyryl-CoA dehydrogenase, mitochondrial ACAD8 Tbio Enzyme -1.14784 13.9 150
Protein O-mannosyl-transferase 1 POMT1 Tbio Enzyme -1.57372 38.3 123
Delta-1-pyrroline-5-carboxylate synthase ALDH18A1 Tbio Enzyme -2.34260 216.5 146
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 Tclin Enzyme -2.43529 263.5 165
EGF-containing fibulin-like extracellular matrix protein 2 EFEMP2 Tbio Non-IDG -1.67314 52.3 243