Development Level

Tbio 54 | 10,625
Tchem 19 | 1,890
Tdark 16 | 7,003
Tclin 3 | 602

Collection

Eligible Ion Channel Proteins 2 | 117

IMPC Term

preweaning lethality, complete... 4 | 633
preweaning lethality, incomple... 4 | 260
embryonic lethality prior to t... 3 | 187
abnormal retinal pigmentation 2 | 61
decreased body weight 2 | 174
embryonic lethality prior to o... 2 | 148
increased mean corpuscular hem... 2 | 93
abnormal behavioral response t... 1 | 52
abnormal coping response 1 | 12
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal spleen morphology 1 | 36
cardiovascular system phenotyp... 1 | 35
decreased B cell number 1 | 30
decreased CD5-positive Ly6C-po... 1 | 4
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C low monocyte nu... 1 | 23
decreased circulating alanine ... 1 | 53
decreased circulating bilirubi... 1 | 14
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased mean platelet volume 1 | 12
decreased monocyte cell number 1 | 28
decreased threshold for audito... 1 | 32
decreased total body fat amoun... 1 | 186
enlarged lymph nodes 1 | 27
immune system phenotype 1 | 17
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased lean body mass 1 | 107
increased mature B cell number 1 | 12
increased mean platelet volume 1 | 19
increased vertical activity 1 | 18
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
thick ventricular wall 1 | 7
tremors 1 | 34

Disease

Muscle Weakness 92 | 92
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 92 | 18,473
Endocrine System 92 | 18,512
Female tissues 92 | 18,647
Nervous System 92 | 18,561
Skin and soft tissues 92 | 18,115
Urinary Tract 92 | 18,444
Blood and immune system 91 | 17,995
Liver and Pancreas 91 | 18,136
Respiratory system 91 | 17,484
Cardiovascular System 90 | 17,958
Male tissues 90 | 17,969

Target Family

Non-IDG 52 | 11,969
Enzyme 19 | 4,146
Transcription Factor 7 | 1,400
Ion Channel 6 | 341
Kinase 4 | 634
Epigenetic 2 | 242
TF/Epigenetic 1 | 38
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein C-ets-2 ETS2 Tbio Transcription Factor -2.39443 244.9 192
Protein dopey-2 DOPEY2 Tbio Non-IDG -0.67912 6.04 14
C2 domain-containing protein 2 C2CD2 Tdark Non-IDG 0.30 0.67 46
A disintegrin and metalloproteinase with thrombospondin motifs 1 ADAMTS1 Tchem Enzyme -2.41810 263.7 203
Chloride intracellular channel protein 6 CLIC6 Tbio Ion Channel -1.03083 11.5 146
ATP-sensitive inward rectifier potassium channel 15 KCNJ15 Tbio Ion Channel -1.29689 20.6 117
Peripheral myelin protein 22 PMP22 Tchem Non-IDG -2.48152 915.8 218
Glutamate receptor ionotropic, kainate 1 GRIK1 Tclin Ion Channel -2.43176 275.1 201
Quinone oxidoreductase-like protein 1 CRYZL1 Tbio Enzyme -1.37951 19.3 127
Interferon gamma receptor 2 IFNGR2 Tbio Non-IDG -1.66522 41.8 211