Development Level

Tbio 1,001 | 11,445
Tchem 132 | 1,598
Tdark 124 | 6,588
Tclin 75 | 613

Collection

RFA-RM-18-021 6 | 328
Kinase: IDG Consortium (Target... 5 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 126 | 979
embryonic lethality prior to o... 38 | 239
preweaning lethality, incomple... 37 | 499
embryonic lethality prior to t... 30 | 278
abnormal embryo size 20 | 220
decreased total body fat amoun... 17 | 207
decreased vertical activity 16 | 208
increased lean body mass 15 | 172
abnormal behavior 14 | 298
cataract 12 | 92
decreased bone mineral content 12 | 151
decreased lean body mass 12 | 135
increased bone mineral content 12 | 108
abnormal retina morphology 11 | 71
decreased bone mineral density 11 | 126
embryonic growth retardation 11 | 106
hypoactivity 11 | 132
prenatal lethality prior to he... 11 | 87
decreased body weight 10 | 161
male infertility 10 | 123
abnormal bone structure 9 | 187
decreased circulating triglyce... 9 | 79
enlarged heart 9 | 210
increased startle reflex 9 | 112
abnormal heart morphology 8 | 162
abnormal lens morphology 8 | 81
decreased lymphocyte cell numb... 8 | 83
increased circulating alkaline... 8 | 122
increased circulating choleste... 8 | 66
increased or absent threshold ... 8 | 101
increased total body fat amoun... 8 | 134
thrombocytopenia 8 | 56
abnormal kidney morphology 7 | 65
decreased leukocyte cell numbe... 7 | 73
increased circulating HDL chol... 7 | 80
increased fasted circulating g... 7 | 76
increased grip strength 7 | 41
abnormal gait 6 | 69
decreased body length 6 | 101
decreased circulating chloride... 6 | 30
decreased circulating insulin ... 6 | 76
decreased neutrophil cell numb... 6 | 42
short tibia 6 | 97
abnormal cranium morphology 5 | 36
abnormal seminal vesicle morph... 5 | 114
abnormal skin morphology 5 | 50
decreased blood urea nitrogen ... 5 | 51
decreased caudal vertebrae num... 5 | 53
decreased grip strength 5 | 116
decreased red blood cell distr... 5 | 41
decreased startle reflex 5 | 75
edema 5 | 59
female infertility 5 | 60
hyperactivity 5 | 148
increased leukocyte cell numbe... 5 | 47
increased neutrophil cell numb... 5 | 46
pallor 5 | 34
abnormal embryo turning 4 | 31
abnormal eye morphology 4 | 68
abnormal skin coloration 4 | 25
abnormal spleen morphology 4 | 55
abnormal testis morphology 4 | 43
decreased circulating HDL chol... 4 | 68
decreased circulating alanine ... 4 | 47
decreased circulating choleste... 4 | 93
decreased circulating glucose ... 4 | 126
decreased circulating sodium l... 4 | 22
decreased circulating total pr... 4 | 49
decreased erythrocyte cell num... 4 | 62
decreased hemoglobin content 4 | 68
decreased mean corpuscular hem... 4 | 31
decreased mean platelet volume 4 | 25
enlarged lymph nodes 4 | 37
improved glucose tolerance 4 | 79
increased bone mineral density 4 | 72
increased circulating bilirubi... 4 | 16
increased circulating chloride... 4 | 41
increased circulating free fat... 4 | 20
increased heart weight 4 | 62
increased hemoglobin content 4 | 45
increased lymphocyte cell numb... 4 | 32
increased mean corpuscular hem... 4 | 96
increased mean corpuscular hem... 4 | 36
increased mean corpuscular vol... 4 | 92
prolonged QT interval 4 | 38
prolonged ST segment 4 | 36
small testis 4 | 58
syndactyly 4 | 23
abnormal coat-hair pigmentatio... 3 | 64
abnormal placenta size 3 | 20
abnormal skin condition 3 | 6
abnormal sleep behavior 3 | 70
abnormal vibrissa morphology 3 | 25
cardiovascular system phenotyp... 3 | 36
corneal opacity 3 | 32
decreased fasted circulating g... 3 | 65
impaired glucose tolerance 3 | 75
increased circulating calcium ... 3 | 34
increased circulating sodium l... 3 | 71
increased prepulse inhibition 3 | 32

Disease

Multiple myeloma 1,332 | 1,332
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 1,313 | 17,369
Endocrine System 1,312 | 18,159
Female tissues 1,312 | 17,400
Skin and soft tissues 1,311 | 17,230
Liver and Pancreas 1,310 | 16,750
Blood and immune system 1,309 | 16,909
Male tissues 1,309 | 17,142
Respiratory system 1,309 | 16,393
Urinary Tract 1,309 | 16,678
Nervous System 1,307 | 16,725
Cardiovascular System 1,299 | 15,192

Target Family

Non-IDG 769 | 12,091
Enzyme 406 | 4,145
Transcription Factor 55 | 1,400
Kinase 42 | 634
Epigenetic 26 | 242
Transporter 22 | 473
GPCR 4 | 408
Ion Channel 4 | 344
TF/Epigenetic 3 | 38
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
Zinc finger protein 160 ZNF160 Tdark Transcription Factor -0.67261 4.33 63
Heterogeneous nuclear ribonucleoprotein H3 HNRNPH3 Tbio Non-IDG -1.80776 63.4 80
60S ribosomal protein L36 RPL36 Tbio Non-IDG -1.62928 39.9 123
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
Unconventional prefoldin RPB5 interactor 1 URI1 Tbio Enzyme -2.15409 134.8 150