Development Level

Tbio 26 | 11,445
Tchem 14 | 1,598
Tclin 13 | 613

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal kidney morphology 3 | 65
embryonic lethality prior to t... 3 | 278
increased circulating alkaline... 3 | 122
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased bone mineral content 2 | 151
decreased circulating choleste... 2 | 93
decreased mean corpuscular vol... 2 | 79
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
enlarged uterus 2 | 11
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
small superior vagus ganglion 2 | 74
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal head morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
edema 1 | 59
enlarged cecum 1 | 5
enlarged kidney 1 | 14
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
long tibia 1 | 25
mammalian phenotype 1 | 17
microphthalmia 1 | 26
vertebral fusion 1 | 23

Disease

Multiple, subcutaneous nodules 53 | 53
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 52 | 17,369
Endocrine System 52 | 18,159
Female tissues 52 | 17,400
Liver and Pancreas 52 | 16,750
Male tissues 52 | 17,142
Nervous System 52 | 16,725
Skin and soft tissues 52 | 17,230
Urinary Tract 52 | 16,678
Blood and immune system 51 | 16,909
Cardiovascular System 51 | 15,192
Respiratory system 51 | 16,393

Target Family

Non-IDG 22 | 12,091
Enzyme 15 | 4,145
Kinase 9 | 634
Transcription Factor 5 | 1,400
GPCR 2 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inner nuclear membrane protein Man1 LEMD3 Tbio Non-IDG -2.30311 196.6 73
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial SDHC Tbio Enzyme -2.73791 419.9 129
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098
Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 Tchem Enzyme -3.19944 1567.0 498
Alpha-galactosidase A GLA Tclin Enzyme -3.00418 985.0 249
Protein ALEX GNAS Tbio Non-IDG -2.63356 1389.7 509
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Alpha-N-acetylgalactosaminidase NAGA Tbio Enzyme -2.21917 159.3 96
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.26377 1794.1 235
Pyrin MEFV Tbio Non-IDG -3.02735 980.3 176