Development Level

Tbio 33 | 11,445
Tclin 13 | 613
Tchem 8 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
abnormal skin morphology 2 | 50
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
enlarged spleen 2 | 41
hyperactivity 2 | 148
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
abnormal allantois morphology 1 | 8
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal left-right axis patte... 1 | 2
abnormal limb bud morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal optic vesicle formati... 1 | 4
abnormal otic vesicle morpholo... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal pharyngeal arch morph... 1 | 8
abnormal somite shape 1 | 5
abnormal tail bud morphology 1 | 8
abnormal tail morphology 1 | 25
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged kidney 1 | 14
enlarged testis 1 | 6
increased bone mineral density 1 | 72
increased circulating fructosa... 1 | 13
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
long tibia 1 | 25
male infertility 1 | 123
pale yolk sac 1 | 25
pallor 1 | 34
shortened QRS complex duration 1 | 1
small epididymis 1 | 3
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

Movement Disorders 55 | 55
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 54 | 18,159
Nervous System 53 | 16,725
Digestive Tract 52 | 17,369
Female tissues 52 | 17,400
Liver and Pancreas 51 | 16,750
Respiratory system 51 | 16,393
Skin and soft tissues 51 | 17,230
Blood and immune system 49 | 16,909
Male tissues 49 | 17,142
Urinary Tract 48 | 16,678
Cardiovascular System 43 | 15,192

Target Family

Non-IDG 26 | 12,091
Enzyme 11 | 4,145
GPCR 6 | 408
Ion Channel 4 | 344
Transcription Factor 4 | 1,400
Transporter 3 | 473
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
Huntingtin HTT Tchem Non-IDG -3.36282 2294.8 599
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Peroxisomal targeting signal 1 receptor PEX5 Tbio Non-IDG -2.43126 272.8 138
Peroxisome biogenesis factor 1 PEX1 Tbio Enzyme -0.77059 5.43 107
Paired box protein Pax-6 PAX6 Tbio Transcription Factor -3.16650 1458.6 570
Kinesin-like protein KIF1A KIF1A Tbio Non-IDG -2.11552 130.9 37
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.14670 1303.9 150
Peroxisome assembly factor 2 PEX6 Tbio Enzyme -1.89379 79.8 148
tRNA-splicing endonuclease subunit Sen34 TSEN34 Tdark Enzyme -0.75841 5.30 26