Development Level

Tbio 57 | 11,178
Tchem 7 | 1,885
Tdark 5 | 6,569
Tclin 3 | 612

IMPC Phenotype

preweaning lethality, complete... 9 | 979
abnormal behavior 4 | 298
decreased body weight 4 | 161
increased circulating alkaline... 4 | 122
preweaning lethality, incomple... 4 | 499
abnormal coat-hair pigmentatio... 3 | 64
abnormal craniofacial morpholo... 3 | 33
abnormal gait 3 | 69
hyperactivity 3 | 148
increased startle reflex 3 | 112
abnormal QT variability 2 | 10
abnormal embryo size 2 | 220
abnormal forebrain morphology 2 | 10
abnormal hindbrain morphology 2 | 10
abnormal midbrain morphology 2 | 10
abnormal neural tube closure 2 | 46
abnormal retina morphology 2 | 71
anophthalmia 2 | 33
decreased circulating aspartat... 2 | 34
decreased lean body mass 2 | 135
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
enlarged lymph nodes 2 | 37
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
prolonged PR interval 2 | 15
syndactyly 2 | 23
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal head size 1 | 6
abnormal limb morphology 1 | 13
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal placement of pupils 1 | 6
abnormal placenta size 1 | 20
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal social-conspecific in... 1 | 3
abnormal tail morphology 1 | 25
abnormal vibrissa morphology 1 | 25
cardiovascular system phenotyp... 1 | 36
cleft palate 1 | 8
decreased B cell number 1 | 5
decreased blood urea nitrogen ... 1 | 51
decreased cardiac stroke volum... 1 | 6
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating potassiu... 1 | 20
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart rate variabili... 1 | 13
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased vertical activity 1 | 208
edema 1 | 59
exencephaly 1 | 2
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased circulating phosphat... 1 | 26
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
long tibia 1 | 25
mammalian phenotype 1 | 17
microphthalmia 1 | 26
mydriasis 1 | 6
narrow eye opening 1 | 12
pallor 1 | 34
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
shortened QT interval 1 | 4
shortened ST segment 1 | 10
small superior vagus ganglion 1 | 74
spina bifida 1 | 2

Disease

Microphthalmia 72 | 72
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 71 | 18,159
Male tissues 63 | 17,142
Skin and soft tissues 63 | 17,230
Female tissues 62 | 17,400
Urinary Tract 61 | 16,678
Digestive Tract 60 | 17,369
Nervous System 60 | 16,725
Blood and immune system 59 | 16,909
Liver and Pancreas 59 | 16,750
Respiratory system 56 | 16,393
Cardiovascular System 52 | 15,192

Target Family

Non-IDG 29 | 12,091
Transcription Factor 23 | 1,400
Enzyme 15 | 4,145
Transporter 2 | 473
Epigenetic 1 | 242
Kinase 1 | 634
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Teneurin-3 TENM3 Tbio Non-IDG -2.01347 99.4 64
Transcription factor E3 TFE3 Tbio Transcription Factor -2.43611 297.2 314
Melanoma antigen recognized by T-cells 1 MLANA Tbio Non-IDG -2.96343 931.7 1096
Transcription factor SOX-10 SOX10 Tbio Transcription Factor -2.69195 478.2 389
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 SMCHD1 Tbio Non-IDG -1.44184 33.6 39
Homeobox protein SIX3 SIX3 Tbio Transcription Factor -2.84681 686.8 212
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
Rho GTPase-activating protein 6 ARHGAP6 Tbio Enzyme -0.85601 8.06 45
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
FRAS1-related extracellular matrix protein 2 FREM2 Tbio Non-IDG -1.25766 15.5 77