Development Level

Tbio 123 | 11,445
Tchem 19 | 1,598
Tdark 19 | 6,588
Tclin 5 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 20 | 979
decreased body weight 8 | 161
embryonic lethality prior to t... 7 | 278
abnormal behavior 6 | 298
embryonic lethality prior to o... 6 | 239
preweaning lethality, incomple... 6 | 499
decreased lean body mass 5 | 135
abnormal embryo size 4 | 220
decreased bone mineral content 4 | 151
decreased total body fat amoun... 4 | 207
increased circulating HDL chol... 4 | 80
increased startle reflex 4 | 112
increased total body fat amoun... 4 | 134
male infertility 4 | 123
prenatal lethality prior to he... 4 | 87
abnormal craniofacial morpholo... 3 | 33
abnormal heart morphology 3 | 162
abnormal tail morphology 3 | 25
anophthalmia 3 | 33
cataract 3 | 92
decreased circulating glucose ... 3 | 126
decreased grip strength 3 | 116
decreased hemoglobin content 3 | 68
decreased startle reflex 3 | 75
decreased vertical activity 3 | 208
hyperactivity 3 | 148
hypoactivity 3 | 132
impaired glucose tolerance 3 | 75
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
limb grasping 3 | 41
thrombocytopenia 3 | 56
abnormal behavioral response t... 2 | 66
abnormal cranium morphology 2 | 36
abnormal eye morphology 2 | 68
abnormal femur morphology 2 | 14
abnormal head morphology 2 | 10
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
absent pinna reflex 2 | 23
cardiovascular system phenotyp... 2 | 36
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 53
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating aspartat... 2 | 34
decreased circulating serum al... 2 | 82
decreased heart rate 2 | 18
decreased leukocyte cell numbe... 2 | 73
edema 2 | 59
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
female infertility 2 | 60
increased body length 2 | 32
increased bone mineral density 2 | 72
increased heart weight 2 | 62
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased prepulse inhibition 2 | 32
microphthalmia 2 | 26
pallor 2 | 34
shortened RR interval 2 | 17
small superior vagus ganglion 2 | 74
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal joint morphology 1 | 23
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal sensory capabilities-... 1 | 8
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal vitreous body morphol... 1 | 10
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased heart left ventricle... 1 | 28
decreased neutrophil cell numb... 1 | 42
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
increased blood urea nitrogen ... 1 | 48
increased cardiac muscle contr... 1 | 8
increased circulating bilirubi... 1 | 16
increased circulating glycerol... 1 | 9
increased circulating phosphat... 1 | 26
increased coping response 1 | 4
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
long tibia 1 | 25
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prolonged RR interval 1 | 8
syndactyly 1 | 23
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Microcephaly 166 | 166
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 161 | 18,159
Digestive Tract 160 | 17,369
Female tissues 158 | 17,400
Male tissues 158 | 17,142
Nervous System 158 | 16,725
Skin and soft tissues 158 | 17,230
Blood and immune system 157 | 16,909
Respiratory system 157 | 16,393
Urinary Tract 157 | 16,678
Liver and Pancreas 156 | 16,750
Cardiovascular System 151 | 15,192

Target Family

Non-IDG 92 | 12,091
Enzyme 38 | 4,145
Transcription Factor 15 | 1,400
Kinase 12 | 634
Transporter 5 | 473
Epigenetic 3 | 242
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin-specific chaperone D TBCD Tbio Non-IDG -1.71996 50.5 50
Protein O-mannosyl-transferase 1 POMT1 Tbio Enzyme -1.57372 38.3 123
Eomesodermin homolog EOMES Tbio Transcription Factor -2.37902 230.4 333
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.94163 8.01 85
Condensin-2 complex subunit G2 NCAPG2 Tbio Non-IDG -0.75957 5.48 110
Heparan sulfate glucosamine 3-O-sulfotransferase 6 HS3ST6 Tdark Enzyme -0.31878 2.19 19
Centlein CNTLN Tbio Non-IDG -2.28518 122.3 76
Rotatin RTTN Tbio Non-IDG -0.87856 9.51 13
Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A Tchem Kinase -2.68760 506.6 336