Development Level

Tbio 25 | 11,445
Tchem 8 | 1,598
Tdark 5 | 6,588
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal seminal vesicle morph... 2 | 114
embryonic lethality prior to t... 2 | 278
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal kidney morphology 1 | 65
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal urinary bladder morph... 1 | 11
abnormal vocalization 1 | 21
decreased bone mineral content 1 | 151
decreased fluid intake 1 | 3
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased heart rate variabili... 1 | 7
increased or absent threshold ... 1 | 101
long tibia 1 | 25
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Meningioma 41 | 41
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 39 | 16,909
Endocrine System 39 | 18,159
Female tissues 39 | 17,400
Male tissues 39 | 17,142
Skin and soft tissues 39 | 17,230
Cardiovascular System 38 | 15,192
Digestive Tract 38 | 17,369
Liver and Pancreas 38 | 16,750
Nervous System 38 | 16,725
Respiratory system 38 | 16,393
Urinary Tract 38 | 16,678

Target Family

Non-IDG 19 | 12,091
Enzyme 12 | 4,145
Kinase 4 | 634
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase TRAF7 TRAF7 Tbio Enzyme -1.09531 13.0 112
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Endonuclease III-like protein 1 NTHL1 Tbio Enzyme -1.85066 66.8 155
Serine/threonine-protein kinase WNK2 WNK2 Tchem Kinase -0.94627 9.07 108
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial SDHC Tbio Enzyme -2.73791 419.9 129
Krueppel-like factor 4 KLF4 Tbio Transcription Factor -2.89447 774.1 686
Transcriptional activator MN1 MN1 Tbio Non-IDG -2.79840 614.5 125
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Cystatin-C CST3 Tbio Non-IDG -3.52815 3278.8 866