Development Level

Tbio 15 | 11,445
Tclin 14 | 613
Tchem 11 | 1,598

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal behavior 3 | 298
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
increased circulating sodium l... 2 | 71
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal limb morphology 1 | 13
abnormal locomotor behavior 1 | 24
abnormal tail morphology 1 | 25
absent vibrissae 1 | 12
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased pulmonary respirator... 1 | 5
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased lymphocyte cell numb... 1 | 32
polycystic kidney 1 | 15
premature death 1 | 5
respiratory system phenotype 1 | 2
tremors 1 | 39

Disease

Memory Disorders 40 | 40
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 40 | 18,159
Nervous System 38 | 16,725
Skin and soft tissues 37 | 17,230
Blood and immune system 35 | 16,909
Digestive Tract 35 | 17,369
Female tissues 35 | 17,400
Urinary Tract 35 | 16,678
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Respiratory system 34 | 16,393
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 15 | 12,091
Enzyme 10 | 4,145
GPCR 7 | 408
Transporter 4 | 473
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 MAGI2 Tbio Enzyme -1.54170 33.0 178
ARF GTPase-activating protein GIT1 GIT1 Tbio Enzyme -1.84352 75.7 358
Sigma non-opioid intracellular receptor 1 SIGMAR1 Tclin Non-IDG -2.28907 210.0 143
5-hydroxytryptamine receptor 6 HTR6 Tchem GPCR -2.31880 213.2 64
Sodium-dependent dopamine transporter SLC6A3 Tclin Transporter -3.59848 3752.4 324
Histamine H3 receptor HRH3 Tclin GPCR -2.76107 570.2 318
Muscarinic acetylcholine receptor M1 CHRM1 Tclin GPCR -2.16159 140.8 222
Pro-neuropeptide Y NPY Tbio Non-IDG -3.83401 7433.3 432
Vesicular glutamate transporter 2 SLC17A6 Tbio Transporter -2.57663 372.2 154
5-hydroxytryptamine receptor 1A HTR1A Tclin GPCR -3.67718 4891.4 254