Development Level

Tbio 143 | 11,651
Tdark 29 | 6,593
Tchem 20 | 1,388
Tclin 14 | 612

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

male infertility 8 | 123
female infertility 5 | 60
decreased bone mineral content 4 | 151
preweaning lethality, incomple... 4 | 499
abnormal bone structure 3 | 187
abnormal heart morphology 3 | 162
decreased bone mineral density 3 | 126
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
improved glucose tolerance 3 | 79
increased circulating alkaline... 3 | 122
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal coat appearance 2 | 31
abnormal gait 2 | 69
abnormal male genitalia morpho... 2 | 3
abnormal startle reflex 2 | 15
decreased circulating alkaline... 2 | 46
decreased circulating iron lev... 2 | 32
decreased circulating triglyce... 2 | 79
decreased lean body mass 2 | 135
decreased vertical activity 2 | 208
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased fasted circulating g... 2 | 76
increased leukocyte cell numbe... 2 | 47
increased total body fat amoun... 2 | 134
thin ventricular wall 2 | 24
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal embryo size 1 | 220
abnormal ileum morphology 1 | 2
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
absent startle reflex 1 | 24
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased brain size 1 | 4
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
fusion of vertebral arches 1 | 7
hydrometra 1 | 53
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lymphocyte cell numb... 1 | 32
limb grasping 1 | 41
oligodactyly 1 | 1
polycystic kidney 1 | 15
polydactyly 1 | 7
polysyndactyly 1 | 2
prenatal lethality prior to he... 1 | 87
prolonged ST segment 1 | 36
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small thymus 1 | 16
vertebral transformation 1 | 12

Disease

Male infertility 206 | 206
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 200 | 18,159
Female tissues 172 | 17,400
Digestive Tract 169 | 17,369
Male tissues 167 | 17,142
Skin and soft tissues 163 | 17,230
Liver and Pancreas 155 | 16,750
Blood and immune system 154 | 16,909
Urinary Tract 152 | 16,678
Respiratory system 147 | 16,393
Nervous System 145 | 16,725
Cardiovascular System 119 | 15,192

Target Family

Non-IDG 118 | 12,091
Enzyme 48 | 4,145
Transcription Factor 11 | 1,400
Kinase 7 | 634
Epigenetic 5 | 242
GPCR 5 | 408
Nuclear Receptor 5 | 48
Ion Channel 4 | 344
TF/Epigenetic 1 | 38
Transporter 1 | 473
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275