Development Level

Tbio 113 | 10,625
Tdark 25 | 7,003
Tchem 20 | 1,890
Tclin 12 | 602

Collection

Ion Channel: IDG Consortium (Targets) 1 | 102
Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
preweaning lethality, incomple... 3 | 260
abnormal bone structure 2 | 131
decreased circulating triglyce... 2 | 83
decreased lean body mass 2 | 195
increased exploration in new e... 2 | 56
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone mineralization 1 | 55
abnormal coat appearance 1 | 25
abnormal gait 1 | 51
abnormal ileum morphology 1 | 2
abnormal lung morphology 1 | 15
abnormal response to tactile s... 1 | 16
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased basophil cell number 1 | 11
decreased brain size 1 | 4
decreased circulating HDL chol... 1 | 77
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating phosphat... 1 | 15
decreased circulating total pr... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased lumbar vertebrae num... 1 | 62
decreased threshold for audito... 1 | 32
enlarged heart 1 | 111
female infertility 1 | 34
fusion of vertebral arches 1 | 7
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased fasted circulating g... 1 | 68
increased lean body mass 1 | 107
increased sacral vertebrae num... 1 | 62
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
male infertility 1 | 62
no abnormal phenotype detected 1 | 3
polycystic kidney 1 | 9
polysyndactyly 1 | 2
shortened PQ interval 1 | 6
shortened PR interval 1 | 5
small heart 1 | 8
small kidney 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small stomach 1 | 3
small thymus 1 | 11
vertebral transformation 1 | 12

Disease

Male infertility 170 | 170
ovarian cancer 8,491 | 8,491
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,098 | 3,098
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,170 | 1,170
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 966 | 966
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 788 | 788
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 764 | 764
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 334 | 334
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Endocrine System 166 | 18,511
Female tissues 166 | 18,646
Urinary Tract 164 | 18,443
Digestive Tract 163 | 18,472
Nervous System 163 | 18,560
Liver and Pancreas 162 | 18,135
Male tissues 159 | 17,968
Skin and soft tissues 158 | 18,114
Cardiovascular System 156 | 17,957
Blood and immune system 155 | 17,994
Respiratory system 142 | 17,483

Target Family

Non-IDG 99 | 11,969
Enzyme 44 | 4,146
Transcription Factor 6 | 1,400
Epigenetic 5 | 242
Ion Channel 4 | 341
Nuclear Receptor 4 | 48
GPCR 3 | 408
Kinase 3 | 634
TF/Epigenetic 1 | 38
oGPCR 1 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.96873 85.2 108
Insulin-like peptide INSL6 INSL6 Tdark Non-IDG -1.08799 12.2 31
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial OXCT2 Tdark Enzyme -0.47712 3.61 56
Cytochrome P450 1A1 CYP1A1 Tchem Non-IDG -3.53853 3553.5 340
Progonadoliberin-1 GNRH1 Tbio Non-IDG -3.57398 3724.8 253
U3 small nucleolar RNA-associated protein 14 homolog C UTP14C Tdark Non-IDG -0.60025 4.82 11
TFIIA-alpha and beta-like factor GTF2A1L Tbio Non-IDG -0.66901 3.86 184
Ubiquitin carboxyl-terminal hydrolase 26 USP26 Tbio Enzyme -1.51447 32.7 53
RNA helicase Mov10l1 MOV10L1 Tbio Enzyme -0.64427 5.20 52
Ubiquitin-conjugating enzyme E2 B UBE2B Tbio Non-IDG -1.56365 38.8 140