Development Level

Tbio 97 | 11,445
Tchem 31 | 1,598
Tclin 19 | 613
Tdark 13 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to o... 6 | 239
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular vol... 3 | 79
embryonic lethality prior to t... 3 | 278
increased circulating sodium l... 3 | 71
abnormal heart morphology 2 | 162
decreased circulating creatini... 2 | 39
decreased neutrophil cell numb... 2 | 42
enlarged heart 2 | 210
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased mean corpuscular vol... 2 | 92
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
increased total body fat amoun... 2 | 134
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal cecum morphology 1 | 7
abnormal coat- hair morphology 1 | 19
abnormal locomotor activation 1 | 16
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased glycosylated hemoglo... 1 | 1
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased red blood cell distr... 1 | 41
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged cecum 1 | 5
enlarged uterus 1 | 11
female infertility 1 | 60
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Malaria 160 | 160
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 149 | 18,159
Female tissues 147 | 17,400
Blood and immune system 146 | 16,909
Skin and soft tissues 145 | 17,230
Digestive Tract 144 | 17,369
Urinary Tract 143 | 16,678
Male tissues 142 | 17,142
Liver and Pancreas 141 | 16,750
Respiratory system 139 | 16,393
Nervous System 137 | 16,725
Cardiovascular System 124 | 15,192

Target Family

Non-IDG 100 | 12,091
Enzyme 38 | 4,145
Ion Channel 5 | 344
Kinase 4 | 634
Transporter 4 | 473
GPCR 3 | 408
oGPCR 3 | 421
Transcription Factor 2 | 1,400
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pyruvate kinase PKLR PKLR Tbio Kinase -2.37549 231.1 391
Unconventional prefoldin RPB5 interactor 1 URI1 Tbio Enzyme -2.15409 134.8 150
Epithelial membrane protein 1 EMP1 Tbio Non-IDG -2.60119 387.7 88
Ankyrin repeat and SOCS box protein 17 ASB17 Tdark Non-IDG -0.64836 4.22 120
Transmembrane protein 64 TMEM64 Tdark Non-IDG -0.22185 1.46 9
Complement receptor type 1 CR1 Tbio Non-IDG -3.36509 2362.6 700
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
Actin-binding protein IPP IPP Tdark Non-IDG -2.93193 840.1 31
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OXSM Tbio Enzyme -1.82909 65.1 127
Sodium channel protein type 3 subunit alpha SCN3A Tclin Ion Channel -1.98160 87.0 76