Development Level

Tbio 103 | 11,445
Tchem 18 | 1,598
Tclin 8 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 16 | 979
abnormal behavior 5 | 298
decreased lean body mass 5 | 135
decreased body weight 4 | 161
embryonic lethality prior to t... 4 | 278
hyperactivity 4 | 148
increased circulating alkaline... 4 | 122
preweaning lethality, incomple... 4 | 499
small superior vagus ganglion 4 | 74
abnormal embryo size 3 | 220
decreased circulating aspartat... 3 | 34
decreased circulating choleste... 3 | 93
decreased circulating serum al... 3 | 82
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
increased startle reflex 3 | 112
short tibia 3 | 97
abnormal femur morphology 2 | 14
abnormal tibia morphology 2 | 14
cataract 2 | 92
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased circulating alanine ... 2 | 47
decreased circulating fructosa... 2 | 30
decreased circulating glucose ... 2 | 126
decreased circulating total pr... 2 | 49
decreased grip strength 2 | 116
decreased heart rate 2 | 18
decreased leukocyte cell numbe... 2 | 73
decreased lymphocyte cell numb... 2 | 83
decreased neutrophil cell numb... 2 | 42
decreased prepulse inhibition 2 | 82
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
hydrometra 2 | 53
impaired glucose tolerance 2 | 75
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
long tibia 2 | 25
prenatal lethality prior to he... 2 | 87
thrombocytopenia 2 | 56
abnormal body wall morphology 1 | 9
abnormal brain morphology 1 | 13
abnormal craniofacial morpholo... 1 | 33
abnormal ear morphology 1 | 9
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
abnormal ulna morphology 1 | 8
cleft palate 1 | 8
decreased blood urea nitrogen ... 1 | 51
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased pulmonary respirator... 1 | 5
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
dilated heart left ventricle 1 | 11
edema 1 | 59
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating alanine ... 1 | 13
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
premature death 1 | 5
prenatal lethality 1 | 28
prolonged RR interval 1 | 8
small testis 1 | 58
thrombocytosis 1 | 27
unresponsive to tactile stimul... 1 | 8
urinary bladder obstruction 1 | 4

Disease

Malar flattening 129 | 129
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 128 | 18,159
Digestive Tract 127 | 17,369
Skin and soft tissues 127 | 17,230
Male tissues 126 | 17,142
Female tissues 125 | 17,400
Liver and Pancreas 125 | 16,750
Nervous System 125 | 16,725
Blood and immune system 124 | 16,909
Respiratory system 123 | 16,393
Urinary Tract 122 | 16,678
Cardiovascular System 118 | 15,192

Target Family

Non-IDG 60 | 12,091
Enzyme 28 | 4,145
Transcription Factor 22 | 1,400
Kinase 9 | 634
Epigenetic 4 | 242
Transporter 3 | 473
GPCR 2 | 408
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cullin-7 CUL7 Tbio Non-IDG -1.49747 38.0 139
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 Tchem Enzyme -1.80418 63.8 91
Nuclear factor 1 X-type NFIX Tbio Transcription Factor -1.70265 49.7 74
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
Leukemia inhibitory factor receptor LIFR Tbio Non-IDG -2.35146 221.3 249
NADPH--cytochrome P450 reductase POR Tbio Enzyme -2.43541 216.2 257
Potassium voltage-gated channel subfamily E regulatory beta subunit 5 KCNE5 Tbio Non-IDG -0.91945 8.20 84
GPI mannosyltransferase 2 PIGV Tbio Enzyme -1.07565 13.4 71
Leucine-rich PPR motif-containing protein, mitochondrial LRPPRC Tbio Non-IDG -1.67434 54.1 80
Zinc finger and BTB domain-containing protein 20 ZBTB20 Tbio Transcription Factor -2.14421 133.1 85