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Development Level

Tbio 55 | 11,445
Tchem 10 | 1,598
Tclin 5 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased total body fat amoun... 3 | 207
impaired glucose tolerance 3 | 75
increased lean body mass 3 | 172
abnormal bone structure 2 | 187
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased grip strength 2 | 116
increased circulating alkaline... 2 | 122
increased or absent threshold ... 2 | 101
increased total body fat amoun... 2 | 134
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal embryo development 1 | 7
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal locomotor behavior 1 | 24
abnormal nail morphology 1 | 8
abnormal response to new envir... 1 | 10
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
absent adrenal gland 1 | 2
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased cardiac output 1 | 3
decreased cardiac stroke volum... 1 | 6
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased pulmonary respirator... 1 | 5
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged stomach 1 | 2
enlarged urinary bladder 1 | 8
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased coping response 1 | 4
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
limb grasping 1 | 41
mammalian phenotype 1 | 17
microphthalmia 1 | 26
pallor 1 | 34
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
short tibia 1 | 97
small thymus 1 | 16
tremors 1 | 39

Disease

Macrostomia 72 | 72
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 72 | 17,369
Endocrine System 72 | 18,159
Nervous System 72 | 16,725
Female tissues 71 | 17,400
Skin and soft tissues 71 | 17,230
Blood and immune system 70 | 16,909
Liver and Pancreas 70 | 16,750
Male tissues 70 | 17,142
Respiratory system 70 | 16,393
Urinary Tract 70 | 16,678
Cardiovascular System 69 | 15,192

Target Family

Non-IDG 36 | 12,091
Enzyme 14 | 4,145
Transcription Factor 8 | 1,400
Kinase 7 | 634
Epigenetic 4 | 242
Ion Channel 2 | 344
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Extracellular matrix protein FRAS1 FRAS1 Tbio Non-IDG -1.51346 36.5 22
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Tyrosine-protein kinase BAZ1B BAZ1B Tbio Epigenetic -1.45627 32.0 155
Bifunctional purine biosynthesis protein PURH ATIC Tchem Non-IDG -2.93014 835.0 246
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
General transcription factor II-I repeat domain-containing protein 1 GTF2IRD1 Tbio Transcription Factor -1.74692 0.00000 281
Ribosomal protein S6 kinase alpha-3 RPS6KA3 Tchem Kinase -2.50143 325.4 425
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Ubiquitin-conjugating enzyme E2 A UBE2A Tbio Non-IDG -1.53597 32.3 117