Development Level

Tbio 47 | 11,651
Tclin 10 | 612
Tchem 8 | 1,388

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 3 | 298
decreased circulating choleste... 2 | 93
decreased exploration in new e... 2 | 11
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal sleep behavior 1 | 70
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating bilirubi... 1 | 19
decreased heart rate 1 | 18
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased urine creatinine lev... 1 | 3
edema 1 | 59
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral density 1 | 72
premature death 1 | 5
prolonged QRS complex duration 1 | 8
small adrenal glands 1 | 16
small lymph nodes 1 | 1
tremors 1 | 39

Disease

Macroglossia 65 | 65
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 64 | 16,909
Endocrine System 64 | 18,159
Nervous System 64 | 16,725
Digestive Tract 62 | 17,369
Female tissues 62 | 17,400
Liver and Pancreas 62 | 16,750
Skin and soft tissues 62 | 17,230
Urinary Tract 62 | 16,678
Male tissues 60 | 17,142
Respiratory system 60 | 16,393
Cardiovascular System 59 | 15,192

Target Family

Enzyme 24 | 4,145
Non-IDG 20 | 12,091
Transcription Factor 7 | 1,400
Kinase 4 | 634
Transporter 3 | 473
Epigenetic 2 | 242
GPCR 2 | 408
Nuclear Receptor 2 | 48
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual oxidase 2 DUOX2 Tbio Enzyme -2.45061 251.8 126
Protein O-mannosyl-transferase 2 POMT2 Tbio Enzyme -1.48456 31.6 104
Tyrosine-protein kinase transmembrane receptor ROR2 ROR2 Tbio Kinase -1.88065 80.4 419
Cullin-4B CUL4B Tbio Non-IDG -1.68710 54.9 251
LIM domain kinase 1 LIMK1 Tchem Kinase -2.28919 187.7 664
Protein Wnt-5a WNT5A Tbio Non-IDG -2.77525 650.2 321
Thyrotropin receptor TSHR Tclin GPCR -3.03356 1166.1 550
Protein O-mannosyl-transferase 1 POMT1 Tbio Enzyme -1.57372 38.3 123
Erythroid transcription factor GATA1 Tbio Transcription Factor -3.00341 967.9 708
Glypican-3 GPC3 Tbio Non-IDG -2.92699 862.1 768