Development Level

Tbio 44 | 11,445
Tchem 12 | 1,598
Tclin 11 | 613

IMPC Phenotype

abnormal behavior 3 | 298
decreased body weight 3 | 161
abnormal cornea morphology 2 | 31
abnormal rib morphology 2 | 10
decreased body length 2 | 101
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased leukocyte cell numbe... 2 | 73
enlarged heart 2 | 210
hypoactivity 2 | 132
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 92
increased thermal nociceptive ... 2 | 9
narrow eye opening 2 | 12
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal eye pigmentation 1 | 3
abnormal eye size 1 | 7
abnormal eyelid aperture 1 | 2
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal iris morphology 1 | 13
abnormal liver morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin condition 1 | 6
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
abnormal vertebral arch morpho... 1 | 9
absent pinna reflex 1 | 23
corneal opacity 1 | 32
corneal vascularization 1 | 6
decreased IgG1 level 1 | 8
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased thermal nociceptive ... 1 | 2
enlarged lymph nodes 1 | 37
excessive tearing 1 | 2
hyperactivity 1 | 148
impaired righting response 1 | 26
increased body weight 1 | 25
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
short tibia 1 | 97
thrombocytosis 1 | 27
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Lymphopenia 67 | 67
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 67 | 18,159
Digestive Tract 66 | 17,369
Male tissues 66 | 17,142
Urinary Tract 66 | 16,678
Blood and immune system 65 | 16,909
Female tissues 65 | 17,400
Skin and soft tissues 65 | 17,230
Liver and Pancreas 64 | 16,750
Respiratory system 64 | 16,393
Cardiovascular System 63 | 15,192
Nervous System 60 | 16,725

Target Family

Non-IDG 36 | 12,091
Enzyme 13 | 4,145
Transcription Factor 7 | 1,400
Kinase 6 | 634
Epigenetic 3 | 242
GPCR 2 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate kinase 2, mitochondrial AK2 Tbio Kinase -2.00007 98.7 330
CTP synthase 1 CTPS1 Tbio Enzyme -2.29349 196.5 107
GTPase IMAP family member 4 GIMAP4 Tbio Enzyme -1.07876 11.0 167
Protein spinster homolog 2 SPNS2 Tbio Non-IDG -1.42853 26.4 88
Tumor necrosis factor ligand superfamily member 12 TNFSF12 Tbio Non-IDG -2.49751 362.7 413
Magnesium transporter protein 1 MAGT1 Tbio Non-IDG -1.60224 37.5 86
V(D)J recombination-activating protein 1 RAG1 Tbio Non-IDG -3.05993 1094.2 84
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.26305 200.9 189
CD81 antigen CD81 Tchem Non-IDG -2.77049 534.4 771
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 SMARCAL1 Tbio Non-IDG -1.74852 65.1 133