Development Level

Tbio 24 | 10,625
Tclin 13 | 602
Tchem 11 | 1,890

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 7 | 633
abnormal embryo size 2 | 112
abnormal body wall morphology 1 | 7
abnormal cranium morphology 1 | 32
abnormal epididymis morphology 1 | 31
abnormal facial morphology 1 | 9
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal neural tube closure 1 | 37
abnormal pelvic girdle bone mo... 1 | 11
abnormal tail morphology 1 | 17
absent vibrissae 1 | 14
cleft palate 1 | 6
decreased KLRG1-positive T-hel... 1 | 2
decreased bone mineral content 1 | 157
decreased circulating free fat... 1 | 39
decreased lean body mass 1 | 195
decreased monocyte cell number 1 | 28
decreased rib number 1 | 59
embryonic growth retardation 1 | 28
enlarged epididymis 1 | 27
enlarged heart 1 | 111
hemorrhage 1 | 12
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating creatini... 1 | 29
increased grip strength 1 | 83
prenatal lethality prior to he... 1 | 64

Disease

Lung diseases 48 | 48
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 48 | 18,473
Liver and Pancreas 48 | 18,136
Nervous System 48 | 18,561
Endocrine System 47 | 18,512
Female tissues 47 | 18,647
Male tissues 47 | 17,969
Respiratory system 47 | 17,484
Skin and soft tissues 47 | 18,115
Urinary Tract 47 | 18,444
Blood and immune system 46 | 17,995
Cardiovascular System 46 | 17,958

Target Family

Non-IDG 18 | 11,969
Enzyme 9 | 4,146
Transcription Factor 9 | 1,400
GPCR 5 | 408
Kinase 5 | 634
Ion Channel 2 | 341

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
AF4/FMR2 family member 4 AFF4 Tbio Transcription Factor -2.52668 332.1 141
Protein sprouty homolog 2 SPRY2 Tbio Non-IDG -1.86730 81.5 178
Krueppel-like factor 2 KLF2 Tbio Transcription Factor -2.23961 188.6 263
C-type lectin domain family 4 member D CLEC4D Tbio Non-IDG -1.38296 21.4 153
Alpha-2-macroglobulin A2M Tbio Non-IDG -2.95602 802.7 553
Vascular endothelial growth factor A VEGFA Tclin Non-IDG -4.24245 17832.7 1361