Development Level

Tbio 126 | 11,178
Tchem 61 | 1,885
Tclin 25 | 612
Tdark 5 | 6,569

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, complete... 12 | 979
enlarged heart 6 | 210
abnormal behavior 5 | 298
abnormal embryo size 5 | 220
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 5 | 499
abnormal heart morphology 4 | 162
decreased vertical activity 4 | 208
abnormal epididymis morphology 3 | 42
abnormal lens morphology 3 | 81
abnormal seminal vesicle morph... 3 | 114
cataract 3 | 92
decreased circulating glucose ... 3 | 126
decreased circulating insulin ... 3 | 76
decreased threshold for audito... 3 | 26
increased bone mineral density 3 | 72
increased neutrophil cell numb... 3 | 46
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
abnormal head morphology 2 | 10
abnormal locomotor behavior 2 | 24
abnormal lung morphology 2 | 26
abnormal startle reflex 2 | 15
abnormal testis morphology 2 | 43
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased erythrocyte cell num... 2 | 62
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular vol... 2 | 79
decreased neutrophil cell numb... 2 | 42
decreased red blood cell distr... 2 | 41
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
enlarged epididymis 2 | 31
increased fasted circulating g... 2 | 76
increased mean corpuscular hem... 2 | 36
male infertility 2 | 123
mammalian phenotype 2 | 17
prenatal lethality prior to he... 2 | 87
small testis 2 | 58
thin ventricular wall 2 | 24
abnormal body wall morphology 1 | 9
abnormal coat appearance 1 | 31
abnormal cornea morphology 1 | 31
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal vasculature m... 1 | 27
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
cleft palate 1 | 8
corneal opacity 1 | 32
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased food intake 1 | 13
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
edema 1 | 59
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
enlarged uterus 1 | 11
female infertility 1 | 60
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased vertical activity 1 | 24
long tibia 1 | 25
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Lung Neoplasms 217 | 217
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Digestive Tract 214 | 17,369
Endocrine System 214 | 18,159
Female tissues 214 | 17,400
Liver and Pancreas 213 | 16,750
Skin and soft tissues 212 | 17,230
Male tissues 211 | 17,142
Blood and immune system 210 | 16,909
Urinary Tract 210 | 16,678
Nervous System 208 | 16,725
Respiratory system 208 | 16,393
Cardiovascular System 195 | 15,192

Target Family

Non-IDG 109 | 12,091
Enzyme 47 | 4,145
Kinase 23 | 634
Transcription Factor 21 | 1,400
Ion Channel 5 | 344
Epigenetic 4 | 242
Transporter 4 | 473
Nuclear Receptor 2 | 48
GPCR 1 | 408
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Wilms tumor protein WT1 Tbio Transcription Factor -3.48344 3138.9 571
Protein CYR61 CYR61 Tbio Non-IDG -2.43164 320.5 423
Prostacyclin synthase PTGIS Tbio Enzyme -2.55019 341.8 152
Acyl-coenzyme A synthetase ACSM1, mitochondrial ACSM1 Tbio Enzyme -2.32216 206.5 61
Cytochrome P450 1B1 CYP1B1 Tchem Non-IDG -2.93702 904.4 260
Homeobox protein EMX2 EMX2 Tbio Transcription Factor -2.04282 110.8 265
Prothymosin alpha PTMA Tbio Non-IDG -2.46161 279.5 211
Cytochrome c oxidase copper chaperone COX17 Tbio Enzyme -1.61452 43.6 157
DNA excision repair protein ERCC-6 ERCC6 Tbio Non-IDG -2.31776 361.5 163
Peroxiredoxin-6 PRDX6 Tbio Non-IDG -2.63290 435.3 425