Development Level

Tclin 39 | 602
Tchem 1 | 1,890

Collection

Eligible Ion Channel Proteins 3 | 117
Eligible non-olfactory GPCR Proteins 1 | 145

IMPC Term

abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal tooth morphology 1 | 24
absent teeth 1 | 4
decreased body weight 1 | 174
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
enlarged heart 1 | 111
increased circulating sodium l... 1 | 71
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
preweaning lethality, complete... 1 | 633
thrombocytopenia 1 | 46

Disease

Local anesthesia 40 | 40
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 40 | 18,473
Nervous System 40 | 18,561
Endocrine System 39 | 18,512
Male tissues 39 | 17,969
Skin and soft tissues 39 | 18,115
Urinary Tract 39 | 18,444
Female tissues 38 | 18,647
Liver and Pancreas 38 | 18,136
Cardiovascular System 37 | 17,958
Blood and immune system 36 | 17,995
Respiratory system 36 | 17,484

Target Family

Ion Channel 30 | 341
GPCR 8 | 408
Non-IDG 1 | 11,969
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 11 subunit alpha SCN11A Tclin Ion Channel -2.44224 238.6 56
Sigma non-opioid intracellular receptor 1 SIGMAR1 Tclin Non-IDG -2.22983 177.5 134
Gamma-aminobutyric acid receptor subunit beta-3 GABRB3 Tclin Ion Channel -2.11058 130.5 161
Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 Tclin Ion Channel -0.94372 8.18 81
Glutamate receptor ionotropic, NMDA 2C GRIN2C Tclin Ion Channel -2.19729 145.4 176
G-protein coupled receptor 39 GPR39 Tchem GPCR -1.72902 59.1 216
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.14144 1336.5 120
Sodium channel protein type 3 subunit alpha SCN3A Tclin Ion Channel -1.94257 73.7 73
Glutamate receptor ionotropic, NMDA 2A GRIN2A Tclin Ion Channel -3.07842 1098.2 460
Glutamate receptor 4 GRIA4 Tclin Ion Channel -2.42299 246.0 294