Development Level

Tbio 480 | 11,178
Tchem 134 | 1,885
Tdark 69 | 6,569
Tclin 50 | 612

Collection

GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 28 | 499
preweaning lethality, complete... 27 | 979
abnormal behavior 15 | 298
enlarged heart 12 | 210
decreased total body fat amoun... 10 | 207
decreased vertical activity 10 | 208
abnormal heart morphology 9 | 162
decreased body weight 9 | 161
decreased circulating glucose ... 9 | 126
decreased grip strength 9 | 116
abnormal seminal vesicle morph... 8 | 114
embryonic lethality prior to o... 8 | 239
embryonic lethality prior to t... 8 | 278
abnormal lens morphology 7 | 81
cataract 7 | 92
short tibia 7 | 97
abnormal coat-hair pigmentatio... 6 | 64
decreased body length 6 | 101
decreased bone mineral content 6 | 151
decreased circulating HDL chol... 6 | 68
decreased circulating choleste... 6 | 93
decreased lean body mass 6 | 135
hypoactivity 6 | 132
increased lean body mass 6 | 172
increased mean corpuscular vol... 6 | 92
abnormal retina morphology 5 | 71
abnormal sleep behavior 5 | 70
decreased bone mineral density 5 | 126
decreased circulating triglyce... 5 | 79
decreased erythrocyte cell num... 5 | 62
edema 5 | 59
hyperactivity 5 | 148
increased bone mineral content 5 | 108
increased bone mineral density 5 | 72
increased circulating HDL chol... 5 | 80
increased fasted circulating g... 5 | 76
increased heart weight 5 | 62
increased mean corpuscular hem... 5 | 96
abnormal bone structure 4 | 187
abnormal testis morphology 4 | 43
decreased blood urea nitrogen ... 4 | 51
decreased circulating LDL chol... 4 | 38
decreased circulating aspartat... 4 | 34
decreased hemoglobin content 4 | 68
decreased leukocyte cell numbe... 4 | 73
decreased lymphocyte cell numb... 4 | 83
decreased mean corpuscular vol... 4 | 79
increased circulating alkaline... 4 | 122
increased circulating choleste... 4 | 66
increased total body fat amoun... 4 | 134
small testis 4 | 58
abnormal embryo size 3 | 220
decreased caudal vertebrae num... 3 | 53
decreased circulating alanine ... 3 | 47
decreased circulating serum al... 3 | 82
decreased heart weight 3 | 27
decreased hematocrit 3 | 46
decreased red blood cell distr... 3 | 41
decreased threshold for audito... 3 | 26
enlarged lymph nodes 3 | 37
impaired glucose tolerance 3 | 75
improved glucose tolerance 3 | 79
increased blood urea nitrogen ... 3 | 48
increased circulating creatini... 3 | 38
increased circulating sodium l... 3 | 71
increased mean corpuscular hem... 3 | 36
increased monocyte cell number 3 | 63
increased or absent threshold ... 3 | 101
increased prepulse inhibition 3 | 32
male infertility 3 | 123
persistence of hyaloid vascula... 3 | 33
small superior vagus ganglion 3 | 74
thrombocytopenia 3 | 56
abnormal behavioral response t... 2 | 66
abnormal craniofacial morpholo... 2 | 33
abnormal cranium morphology 2 | 36
abnormal eye morphology 2 | 68
abnormal gait 2 | 69
abnormal lung morphology 2 | 26
abnormal tooth morphology 2 | 24
abnormal vocalization 2 | 21
decreased IgG1 level 2 | 8
decreased circulating creatini... 2 | 39
decreased circulating insulin ... 2 | 76
decreased circulating iron lev... 2 | 32
decreased circulating sodium l... 2 | 22
decreased circulating total pr... 2 | 49
decreased eosinophil cell numb... 2 | 24
embryonic growth retardation 2 | 106
impaired pupillary reflex 2 | 26
increased body length 2 | 32
increased body weight 2 | 25
increased circulating chloride... 2 | 41
increased circulating phosphat... 2 | 26
increased hemoglobin content 2 | 45
increased red blood cell distr... 2 | 34
increased startle reflex 2 | 112
long tibia 2 | 25
thrombocytosis 2 | 27
tremors 2 | 39

Disease

Liver Cirrhosis, Experimental 733 | 733
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 723 | 18,159
Liver and Pancreas 723 | 16,750
Digestive Tract 719 | 17,369
Urinary Tract 717 | 16,678
Female tissues 715 | 17,400
Skin and soft tissues 712 | 17,230
Blood and immune system 711 | 16,909
Male tissues 710 | 17,142
Nervous System 706 | 16,725
Respiratory system 698 | 16,393
Cardiovascular System 676 | 15,192

Target Family

Non-IDG 423 | 12,091
Enzyme 199 | 4,145
Kinase 29 | 634
Transporter 28 | 473
Transcription Factor 25 | 1,400
GPCR 14 | 408
Ion Channel 9 | 344
Epigenetic 3 | 242
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hydroxyacylglutathione hydrolase, mitochondrial HAGH Tbio Enzyme -1.95974 82.6 162
Nidogen-2 NID2 Tbio Non-IDG -1.62355 40.1 116
Solute carrier family 22 member 8 SLC22A8 Tclin Transporter -2.40126 258.4 113
Neutrophil gelatinase-associated lipocalin LCN2 Tbio Enzyme -3.35178 2368.1 847
Nck-associated protein 1-like NCKAP1L Tbio Non-IDG -1.07556 11.2 127
2-5A-dependent ribonuclease RNASEL Tchem Kinase -2.71673 525.8 127
Protein canopy homolog 4 CNPY4 Tdark Non-IDG -0.25487 1.75 27
Macrophage colony-stimulating factor 1 receptor CSF1R Tclin Kinase -3.19109 1432.9 1169
Protein RMD5 homolog B RMND5B Tdark Non-IDG -0.60206 3.47 69
Cell surface glycoprotein CD200 receptor 1 CD200R1 Tbio Non-IDG -1.93142 83.6 476