Development Level

Tbio 54 | 10,625
Tchem 29 | 1,890
Tclin 14 | 602
Tdark 4 | 7,003

IMPC Term

decreased bone mineral content 4 | 157
hypoactivity 4 | 89
preweaning lethality, complete... 4 | 633
preweaning lethality, incomple... 4 | 260
abnormal behavior 3 | 226
decreased body weight 3 | 174
decreased grip strength 3 | 123
decreased lean body mass 3 | 195
abnormal bone structure 2 | 131
abnormal lens morphology 2 | 73
cataract 2 | 26
decreased body length 2 | 108
decreased circulating insulin ... 2 | 75
decreased circulating iron lev... 2 | 25
decreased circulating triglyce... 2 | 83
decreased mean corpuscular hem... 2 | 34
decreased mean corpuscular hem... 2 | 19
decreased mean corpuscular vol... 2 | 50
impaired righting response 2 | 19
improved glucose tolerance 2 | 56
increased body weight 2 | 42
increased fasted circulating g... 2 | 68
abnormal bone mineralization 1 | 55
abnormal coat/hair pigmentatio... 1 | 54
abnormal coping response 1 | 12
abnormal eye morphology 1 | 38
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 51
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 2
abnormal liver morphology 1 | 5
abnormal lung morphology 1 | 15
abnormal response to tactile s... 1 | 16
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 17
absent startle reflex 1 | 15
decreased T cell number 1 | 31
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased fasted circulating g... 1 | 49
decreased food intake 1 | 6
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased kidney weight 1 | 7
decreased lumbar vertebrae num... 1 | 62
decreased mean platelet volume 1 | 12
decreased prepulse inhibition 1 | 52
decreased respiratory quotient 1 | 12
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
enlarged heart 1 | 111
enlarged liver 1 | 3
enlarged lymph nodes 1 | 27
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating chloride... 1 | 43
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased lean body mass 1 | 107
increased or absent threshold ... 1 | 128
increased respiratory quotient 1 | 12
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
limb grasping 1 | 35
male infertility 1 | 62
mydriasis 1 | 9
prenatal lethality prior to he... 1 | 64
shortened QRS complex duration 1 | 1
tremors 1 | 34

Disease

Liver Cirrhosis 101 | 101
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 99 | 18,473
Endocrine System 99 | 18,512
Female tissues 99 | 18,647
Nervous System 99 | 18,561
Skin and soft tissues 99 | 18,115
Urinary Tract 98 | 18,444
Blood and immune system 97 | 17,995
Liver and Pancreas 97 | 18,136
Cardiovascular System 96 | 17,958
Male tissues 94 | 17,969
Respiratory system 94 | 17,484

Target Family

Non-IDG 56 | 11,971
Enzyme 23 | 4,146
GPCR 7 | 406
Transcription Factor 6 | 1,400
Kinase 4 | 634
Transporter 3 | 473
Ion Channel 1 | 341
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Glypican-3 GPC3 Tbio Non-IDG -2.85848 794.8 523
Galectin-3-binding protein LGALS3BP Tbio Non-IDG -2.79457 669.7 172
Vitamin D-binding protein GC Tchem Non-IDG -3.02965 1072.9 365
Serpin H1 SERPINH1 Tbio Non-IDG -3.13545 1424.1 295
Alpha-fetoprotein AFP Tbio Non-IDG -4.04711 11505.1 1715
Interferon lambda-3 IFNL3 Tbio Non-IDG -3.04964 1189.7 153
rRNA 2'-O-methyltransferase fibrillarin FBL Tbio Enzyme -3.17750 1580.2 240
Alpha-1A adrenergic receptor ADRA1A Tclin GPCR -2.16676 150.4 223
Fibroblast growth factor 2 FGF2 Tchem Non-IDG -3.97848 10115.4 658