Development Level

Tbio 125 | 11,651
Tchem 35 | 1,388
Tclin 18 | 612
Tdark 3 | 6,593

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 11 | 499
decreased total body fat amoun... 6 | 207
abnormal behavior 4 | 298
impaired righting response 4 | 26
increased startle reflex 4 | 112
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating glucose ... 3 | 126
decreased circulating insulin ... 3 | 76
decreased circulating triglyce... 3 | 79
decreased mean corpuscular vol... 3 | 79
decreased vertical activity 3 | 208
enlarged heart 3 | 210
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
increased circulating iron lev... 3 | 30
increased total body fat amoun... 3 | 134
abnormal bone mineralization 2 | 38
abnormal gait 2 | 69
abnormal lung morphology 2 | 26
abnormal tooth morphology 2 | 24
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating amylase ... 2 | 28
decreased circulating iron lev... 2 | 32
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased food intake 2 | 13
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 31
impaired glucose tolerance 2 | 75
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
increased neutrophil cell numb... 2 | 46
persistence of hyaloid vascula... 2 | 33
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo turning 1 | 31
abnormal head morphology 1 | 10
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
short tibia 1 | 97
stereotypic behavior 1 | 3
thin ventricular wall 1 | 24
tremors 1 | 39
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Liver Cirrhosis 181 | 181
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 174 | 18,159
Digestive Tract 172 | 17,369
Skin and soft tissues 168 | 17,230
Blood and immune system 167 | 16,909
Female tissues 166 | 17,400
Liver and Pancreas 166 | 16,750
Male tissues 166 | 17,142
Urinary Tract 166 | 16,678
Nervous System 162 | 16,725
Respiratory system 159 | 16,393
Cardiovascular System 155 | 15,192

Target Family

Non-IDG 97 | 12,091
Enzyme 45 | 4,145
Transcription Factor 10 | 1,400
Transporter 9 | 473
GPCR 8 | 408
Kinase 8 | 634
Epigenetic 1 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Probable allantoicase ALLC Tdark Enzyme -2.87521 709.7 0
G-protein coupled receptor 176 GPR176 Tbio GPCR -2.38327 235.4 133
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Laminin subunit gamma-2 LAMC2 Tbio Non-IDG -2.09168 112.5 175
Protein Mpv17 MPV17 Tbio Non-IDG -1.67807 47.6 134
Protein-lysine 6-oxidase LOX Tbio Enzyme -3.36257 2227.1 513
TERF1-interacting nuclear factor 2 TINF2 Tbio Non-IDG -2.03707 99.1 138
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222