Development Level

Tbio 107 | 11,178
Tchem 45 | 1,885
Tclin 18 | 612
Tdark 3 | 6,569

Collection

GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 11 | 499
decreased total body fat amoun... 6 | 207
abnormal behavior 4 | 298
impaired righting response 4 | 26
increased startle reflex 4 | 112
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased circulating glucose ... 3 | 126
decreased circulating insulin ... 3 | 76
decreased circulating triglyce... 3 | 79
decreased mean corpuscular vol... 3 | 79
decreased vertical activity 3 | 208
enlarged heart 3 | 210
hypoactivity 3 | 132
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
increased total body fat amoun... 3 | 134
abnormal bone mineralization 2 | 38
abnormal gait 2 | 69
abnormal lung morphology 2 | 26
abnormal tooth morphology 2 | 24
decreased body length 2 | 101
decreased body weight 2 | 161
decreased circulating amylase ... 2 | 28
decreased circulating iron lev... 2 | 32
decreased fasted circulating g... 2 | 65
decreased food intake 2 | 13
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 31
impaired glucose tolerance 2 | 75
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating iron lev... 2 | 30
increased heart weight 2 | 62
increased lean body mass 2 | 172
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 36
increased neutrophil cell numb... 2 | 46
persistence of hyaloid vascula... 2 | 33
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo turning 1 | 31
abnormal head morphology 1 | 10
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
dilated heart left ventricle 1 | 11
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
limb grasping 1 | 41
short tibia 1 | 97
stereotypic behavior 1 | 3
thin ventricular wall 1 | 24
tremors 1 | 39
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Liver Cirrhosis 173 | 173
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 166 | 18,159
Digestive Tract 164 | 17,369
Skin and soft tissues 161 | 17,230
Blood and immune system 159 | 16,909
Male tissues 159 | 17,142
Urinary Tract 159 | 16,678
Female tissues 158 | 17,400
Liver and Pancreas 158 | 16,750
Nervous System 154 | 16,725
Respiratory system 152 | 16,393
Cardiovascular System 148 | 15,192

Target Family

Non-IDG 94 | 12,091
Enzyme 42 | 4,145
Transporter 9 | 473
GPCR 8 | 408
Kinase 8 | 634
Transcription Factor 8 | 1,400
Epigenetic 1 | 242
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cannabinoid receptor 2 CNR2 Tchem GPCR -2.45761 269.7 345
Solute carrier family 22 member 8 SLC22A8 Tclin Transporter -2.40126 258.4 113
Tumor necrosis factor receptor superfamily member 1B TNFRSF1B Tchem Non-IDG -3.67481 4484.7 712
Uncharacterized protein C6orf10 C6orf10 Tdark Non-IDG -0.51955 3.93 23
Probable G-protein coupled receptor 148 GPR148 Tdark GPCR -2.16209 149.1 32
Vitamin D 25-hydroxylase CYP2R1 Tbio Enzyme -1.96830 95.4 152
Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 Tchem Enzyme -3.04846 1171.6 189
Regucalcin RGN Tbio Non-IDG -2.61474 478.2 85
7-dehydrocholesterol reductase DHCR7 Tchem Enzyme -2.44252 276.5 109
Nitric oxide synthase, endothelial NOS3 Tchem Enzyme -3.96497 9525.3 1195