Development Level

Tbio 78 | 10,625
Tchem 23 | 1,890
Tclin 11 | 602
Tdark 1 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
decreased bone mineral density 3 | 126
abnormal coat/hair pigmentatio... 2 | 54
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
enlarged heart 2 | 111
enlarged spleen 2 | 26
increased lean body mass 2 | 107
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal gait 1 | 51
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 2
abnormal lens morphology 1 | 73
abnormal ovary morphology 1 | 3
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal thoracic vertebrae mo... 1 | 16
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 17
absent epididymis 1 | 2
cataract 1 | 26
decreased B cell number 1 | 30
decreased CD4-positive, CD25-p... 1 | 24
decreased CD8-positive, naive ... 1 | 5
decreased body length 1 | 108
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased effector memory CD8-... 1 | 24
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lactate dehydrogenas... 1 | 14
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 19
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged ovary 1 | 1
hyperactivity 1 | 108
improved glucose tolerance 1 | 56
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased KLRG1+ CD8 alpha bet... 1 | 2
increased KLRG1-positive CD4-n... 1 | 1
increased KLRG1-positive CD4-p... 1 | 3
increased KLRG1-positive NK ce... 1 | 9
increased KLRG1-positive T-hel... 1 | 2
increased KLRG1-positive gamma... 1 | 2
increased Ly6C low monocyte nu... 1 | 8
increased NK cell number 1 | 19
increased body length 1 | 20
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating alanine ... 1 | 11
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased effector memory T-he... 1 | 5
increased eosinophil cell numb... 1 | 9
increased exploration in new e... 1 | 56
increased heart rate 1 | 17
increased memory CD4-positive,... 1 | 3
increased memory-marker CD4-ne... 1 | 1
increased monocyte cell number 1 | 27
increased myeloid cell number 1 | 2
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
increased vertical activity 1 | 18
iris synechia 1 | 1
male infertility 1 | 62
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
shortened PQ interval 1 | 6
shortened RR interval 1 | 19
thick ventricular wall 1 | 7

Disease

Leukemia, Myelocytic, Acute 113 | 113
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Blood and immune system 113 | 17,995
Cardiovascular System 113 | 17,958
Digestive Tract 113 | 18,473
Endocrine System 113 | 18,512
Female tissues 113 | 18,647
Liver and Pancreas 113 | 18,136
Nervous System 113 | 18,561
Urinary Tract 113 | 18,444
Respiratory system 112 | 17,484
Skin and soft tissues 112 | 18,115
Male tissues 111 | 17,969

Target Family

Non-IDG 58 | 11,971
Transcription Factor 20 | 1,400
Enzyme 15 | 4,146
Kinase 10 | 634
Epigenetic 6 | 242
GPCR 2 | 406
Ion Channel 1 | 341
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.21148 186.3 172
Tumor necrosis factor receptor superfamily member 6 FAS Tbio Non-IDG -3.27492 2052.7 1794
Lipoma-preferred partner LPP Tbio Non-IDG -2.68601 520.6 153
Tubulin beta-2A chain TUBB2A Tclin Non-IDG -1.58651 36.1 215
Transcriptional regulator ERG ERG Tchem Transcription Factor -2.49936 317.4 284
GMP synthase [glutamine-hydrolyzing] GMPS Tchem Enzyme -2.43758 281.7 169
Catenin alpha-1 CTNNA1 Tbio Non-IDG -1.91334 73.6 399
Tuberin TSC2 Tbio Non-IDG -2.94615 933.5 1483
cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B Tclin Enzyme -2.10700 124.5 270