Development Level

Tbio 87 | 11,445
Tchem 20 | 1,598
Tclin 12 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 5 | 499
abnormal behavior 3 | 298
decreased bone mineral density 3 | 126
abnormal bone structure 2 | 187
abnormal coat-hair pigmentatio... 2 | 64
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating choleste... 2 | 93
decreased circulating insulin ... 2 | 76
decreased grip strength 2 | 116
decreased heart rate 2 | 18
decreased leukocyte cell numbe... 2 | 73
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
enlarged spleen 2 | 41
impaired glucose tolerance 2 | 75
increased lean body mass 2 | 172
increased startle reflex 2 | 112
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal epididymis morphology 1 | 42
abnormal eye size 1 | 7
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal ovary morphology 1 | 7
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
absent epididymis 1 | 3
cataract 1 | 92
decreased body length 1 | 101
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged ovary 1 | 2
hemorrhage 1 | 23
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alanine ... 1 | 13
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
iris synechia 1 | 3
long tibia 1 | 25
male infertility 1 | 123
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
prolonged RR interval 1 | 8
shortened PQ interval 1 | 7
shortened RR interval 1 | 17
small spleen 1 | 19
thick ventricular wall 1 | 7
tremors 1 | 39
trunk curl 1 | 16

Disease

Leukemia, Myelocytic, Acute 120 | 120
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 120 | 16,909
Digestive Tract 120 | 17,369
Endocrine System 120 | 18,159
Female tissues 120 | 17,400
Skin and soft tissues 120 | 17,230
Male tissues 119 | 17,142
Respiratory system 119 | 16,393
Liver and Pancreas 118 | 16,750
Nervous System 118 | 16,725
Urinary Tract 118 | 16,678
Cardiovascular System 113 | 15,192

Target Family

Non-IDG 61 | 12,091
Transcription Factor 22 | 1,400
Enzyme 15 | 4,145
Kinase 10 | 634
Epigenetic 8 | 242
GPCR 2 | 408
Ion Channel 1 | 344
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-lysine N-methyltransferase NSD3 NSD3 Tbio Epigenetic -1.36629 23.0 234
Cystatin-C CST3 Tbio Non-IDG -3.52815 3278.8 866
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.90906 89.8 184
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Transcription factor PU.1 SPI1 Tbio Transcription Factor -3.05079 1139.0 397
Zinc finger protein Gfi-1 GFI1 Tbio Transcription Factor -2.20783 172.7 176
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 DHX15 Tbio Enzyme -1.74929 55.5 106
Endophilin-A2 SH3GL1 Tbio Non-IDG -2.15479 134.2 257
Cysteine-rich hydrophobic domain-containing protein 2 CHIC2 Tbio Non-IDG -2.12710 132.1 97
Brain and acute leukemia cytoplasmic protein BAALC Tbio Non-IDG -1.65293 47.9 117