Development Level

Tbio 71 | 11,651
Tchem 21 | 1,388
Tclin 6 | 612
Tdark 6 | 6,593

IMPC Phenotype

preweaning lethality, complete... 11 | 979
increased lean body mass 4 | 172
increased total body fat amoun... 3 | 134
limb grasping 3 | 41
abnormal embryo size 2 | 220
abnormal locomotor activation 2 | 16
abnormal startle reflex 2 | 15
abnormal tooth morphology 2 | 24
decreased body weight 2 | 161
decreased circulating iron lev... 2 | 32
decreased erythrocyte cell num... 2 | 62
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
impaired glucose tolerance 2 | 75
increased blood urea nitrogen ... 2 | 48
increased circulating amylase ... 2 | 25
increased circulating aspartat... 2 | 15
increased circulating creatine... 2 | 5
increased startle reflex 2 | 112
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
absent ovary 1 | 3
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating creatine... 1 | 4
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
decreased kidney weight 1 | 1
decreased leukocyte cell numbe... 1 | 73
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
long tibia 1 | 25
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
prolonged QRS complex duration 1 | 8
small testis 1 | 58
thick ventricular wall 1 | 7
thrombocytopenia 1 | 56

Disease

Leukemia 104 | 104
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 98 | 17,369
Endocrine System 98 | 18,159
Female tissues 98 | 17,400
Blood and immune system 97 | 16,909
Male tissues 97 | 17,142
Skin and soft tissues 97 | 17,230
Liver and Pancreas 96 | 16,750
Urinary Tract 96 | 16,678
Nervous System 95 | 16,725
Respiratory system 95 | 16,393
Cardiovascular System 93 | 15,192

Target Family

Non-IDG 50 | 12,091
Enzyme 21 | 4,145
Transcription Factor 13 | 1,400
Epigenetic 9 | 242
Kinase 7 | 634
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CCAAT/enhancer-binding protein epsilon CEBPE Tbio Transcription Factor -1.71776 57.4 246
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
T-cell leukemia/lymphoma protein 1B TCL1B Tdark Non-IDG -1.17863 16.3 34
Nuclear receptor coactivator 3 NCOA3 Tbio Epigenetic -2.64583 480.2 417
Sphingomyelin phosphodiesterase 3 SMPD3 Tbio Enzyme -1.84613 78.5 126
T-cell surface protein tactile CD96 Tbio Non-IDG -2.05505 111.7 205
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
Protein CBFA2T2 CBFA2T2 Tbio Non-IDG -1.07203 12.0 216
Sphingosine kinase 1 SPHK1 Tchem Kinase -2.72994 583.6 518
Tumor necrosis factor ligand superfamily member 10 TNFSF10 Tbio Non-IDG -2.87006 661.9 949