Development Level

Tbio 56 | 10,625
Tchem 20 | 1,890
Tdark 7 | 7,003
Tclin 5 | 602

IMPC Term

preweaning lethality, complete... 4 | 633
decreased lean body mass 3 | 195
decreased total body fat amoun... 3 | 186
limb grasping 3 | 35
abnormal bone mineralization 2 | 55
abnormal locomotor activation 2 | 26
abnormal startle reflex 2 | 14
abnormal tooth morphology 2 | 24
decreased body weight 2 | 174
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 85
decreased circulating iron lev... 2 | 25
decreased erythrocyte cell num... 2 | 43
decreased hematocrit 2 | 25
decreased hemoglobin content 2 | 53
decreased prepulse inhibition 2 | 52
increased blood urea nitrogen ... 2 | 44
increased circulating amylase ... 2 | 13
increased grip strength 2 | 83
increased lean body mass 2 | 107
preweaning lethality, incomple... 2 | 260
abnormal bone structure 1 | 131
abnormal response to new envir... 1 | 8
abnormal retina morphology 1 | 100
abnormal spleen morphology 1 | 36
absent ovary 1 | 2
decreased B cell number 1 | 30
decreased CD4-positive, CD25-p... 1 | 24
decreased NK T cell number 1 | 28
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating creatini... 1 | 31
decreased fasted circulating g... 1 | 49
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased mean corpuscular vol... 1 | 50
enlarged heart 1 | 111
impaired glucose tolerance 1 | 52
increased KLRG1-positive CD4-p... 1 | 2
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating choleste... 1 | 53
increased circulating iron lev... 1 | 25
increased effector memory CD4-... 1 | 15
increased exploration in new e... 1 | 56
increased granulocyte number 1 | 8
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased pre-pro B cell numbe... 1 | 2
increased sacral vertebrae num... 1 | 62
persistence of hyaloid vascula... 1 | 22
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
prolonged PR interval 1 | 4
prolonged QRS complex duration 1 | 2
short tibia 1 | 82
thick ventricular wall 1 | 7
thrombocytopenia 1 | 46

Disease

Leukemia 88 | 88
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Blood and immune system 82 | 17,995
Digestive Tract 82 | 18,473
Endocrine System 82 | 18,512
Nervous System 82 | 18,561
Female tissues 81 | 18,647
Male tissues 81 | 17,969
Respiratory system 81 | 17,484
Skin and soft tissues 81 | 18,115
Urinary Tract 81 | 18,444
Cardiovascular System 80 | 17,958
Liver and Pancreas 80 | 18,136

Target Family

Non-IDG 43 | 11,971
Enzyme 16 | 4,146
Transcription Factor 15 | 1,400
Epigenetic 7 | 242
Kinase 3 | 634
Nuclear Receptor 2 | 48
TF/Epigenetic 2 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Interleukin-15 IL15 Tbio Non-IDG -3.01964 1248.2 612
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.21148 186.3 172
Very-long-chain enoyl-CoA reductase TECR Tbio Enzyme -2.58601 380.5 85
Transmembrane protein 132D TMEM132D Tbio Non-IDG -2.20806 159.4 59
Ig lambda-7 chain C region IGLC7 Tdark Non-IDG 228.7 0
Protein CBFA2T3 CBFA2T3 Tbio Non-IDG -1.75413 60.7 65
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.81595 662.3 551
Transcriptional regulator ERG ERG Tchem Transcription Factor -2.49936 317.4 284
Alpha-2,8-sialyltransferase 8F ST8SIA6 Tdark Enzyme -0.40796 3.37 63