Development Level

Tbio 55 | 10,625
Tchem 11 | 1,890
Tclin 5 | 602
Tdark 1 | 7,003

IMPC Term

increased circulating alkaline... 4 | 119
abnormal behavior 3 | 226
abnormal retina morphology 3 | 100
hyperactivity 3 | 108
preweaning lethality, incomple... 3 | 260
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
decreased circulating free fat... 2 | 39
decreased circulating glycerol... 2 | 19
increased circulating alanine ... 2 | 11
increased circulating aspartat... 2 | 17
increased circulating sodium l... 2 | 71
increased mean corpuscular vol... 2 | 91
increased or absent threshold ... 2 | 128
limb grasping 2 | 35
preweaning lethality, complete... 2 | 633
abnormal anxiety-related respo... 1 | 1
abnormal glucose homeostasis 1 | 5
abnormal kidney morphology 1 | 30
abnormal locomotor activation 1 | 26
abnormal lung morphology 1 | 15
abnormal lymph node morphology 1 | 3
abnormal respiratory quotient 1 | 9
abnormal retinal pigmentation 1 | 61
abnormal social/conspecific in... 1 | 3
abnormal spine curvature 1 | 7
absent pinna reflex 1 | 21
absent vibrissae 1 | 14
decreased CD4-positive, alpha ... 1 | 19
decreased body length 1 | 108
decreased body weight 1 | 174
decreased circulating HDL chol... 1 | 77
decreased circulating amylase ... 1 | 24
decreased circulating calcium ... 1 | 33
decreased circulating choleste... 1 | 85
decreased circulating creatini... 1 | 31
decreased circulating serum al... 1 | 79
decreased circulating triglyce... 1 | 83
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
hypoactivity 1 | 89
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
increased NK T cell number 1 | 11
increased blood urea nitrogen ... 1 | 44
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating potassiu... 1 | 31
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased lactate dehydrogenas... 1 | 3
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased sacral vertebrae num... 1 | 62
mydriasis 1 | 9
persistence of hyaloid vascula... 1 | 22
stereotypic behavior 1 | 3
trunk curl 1 | 15
vertebral fusion 1 | 23

Disease

Leber congenital amaurosis 72 | 72
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 72 | 18,473
Endocrine System 72 | 18,512
Nervous System 72 | 18,561
Skin and soft tissues 72 | 18,115
Female tissues 71 | 18,647
Liver and Pancreas 71 | 18,136
Urinary Tract 71 | 18,444
Respiratory system 70 | 17,484
Blood and immune system 69 | 17,995
Cardiovascular System 69 | 17,958
Male tissues 69 | 17,969

Target Family

Non-IDG 34 | 11,971
Enzyme 20 | 4,146
Kinase 5 | 634
Ion Channel 3 | 341
Nuclear Receptor 3 | 48
Transcription Factor 3 | 1,400
GPCR 2 | 406
Transporter 2 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centrosomal protein of 290 kDa CEP290 Tbio Non-IDG -1.97186 101.3 125
Retinoschisin RS1 Tbio Non-IDG -2.46364 308.0 22
Alpha-(1,3)-fucosyltransferase 4 FUT4 Tbio Enzyme -3.08185 1189.5 813
Lysozyme C LYZ Tbio Enzyme -3.63761 4321.0 420
Nephrocystin-4 NPHP4 Tbio Non-IDG -1.39275 26.0 48
Retinal guanylyl cyclase 2 GUCY2F Tbio Kinase -1.03655 7.37 72
Peroxisome biogenesis factor 1 PEX1 Tbio Enzyme -0.69037 4.43 94
Neural cell adhesion molecule 1 NCAM1 Tchem Non-IDG -3.50984 3805.8 1530
Beta-galactosidase-1-like protein 3 GLB1L3 Tdark Enzyme 0.35 0.72 81
Intraflagellar transport protein 140 homolog IFT140 Tbio Non-IDG -1.25967 18.3 40