Development Level

Tbio 52 | 11,445
Tchem 11 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased circulating serum al... 3 | 82
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
abnormal retina morphology 2 | 71
decreased body weight 2 | 161
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
enlarged heart 2 | 210
hyperactivity 2 | 148
increased blood urea nitrogen ... 2 | 48
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
preweaning lethality, incomple... 2 | 499
abnormal anxiety-related respo... 1 | 1
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal locomotor activation 1 | 16
abnormal lung morphology 1 | 26
abnormal lymph node morphology 1 | 3
abnormal pupil morphology 1 | 2
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin morphology 1 | 50
abnormal social-conspecific in... 1 | 3
abnormal spine curvature 1 | 9
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased startle reflex 1 | 75
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased circulating alanine ... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating aspartat... 1 | 15
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased circulating unsatura... 1 | 1
increased exploration in new e... 1 | 8
increased heart weight 1 | 62
increased lactate dehydrogenas... 1 | 3
increased mean corpuscular hem... 1 | 96
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
stereotypic behavior 1 | 3
thin ventricular wall 1 | 24
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Leber congenital amaurosis 69 | 69
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 68 | 18,159
Skin and soft tissues 66 | 17,230
Digestive Tract 65 | 17,369
Blood and immune system 64 | 16,909
Female tissues 63 | 17,400
Male tissues 63 | 17,142
Liver and Pancreas 62 | 16,750
Nervous System 59 | 16,725
Urinary Tract 59 | 16,678
Respiratory system 54 | 16,393
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 30 | 12,091
Enzyme 22 | 4,145
Kinase 4 | 634
Ion Channel 3 | 344
Nuclear Receptor 3 | 48
Transcription Factor 3 | 1,400
GPCR 2 | 408
Transporter 2 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Cone-rod homeobox protein CRX Tbio Transcription Factor -2.44826 272.0 185
NEDD8 ultimate buster 1 NUB1 Tbio Non-IDG -1.81251 65.2 0
Retinal guanylyl cyclase 1 GUCY2D Tbio Kinase -2.20658 167.7 205
Neural retina-specific leucine zipper protein NRL Tbio Transcription Factor -2.46080 279.4 74
Centlein CNTLN Tbio Non-IDG -2.28518 122.3 76
Tyrosine-protein kinase Mer MERTK Tchem Kinase -2.27276 199.1 609
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Aryl-hydrocarbon-interacting protein-like 1 AIPL1 Tbio Non-IDG -1.73867 59.0 229
Guanylyl cyclase-activating protein 2 GUCA1B Tbio Enzyme -1.63232 42.4 122