Development Level

Tbio 50 | 10,625
Tchem 20 | 1,890
Tclin 12 | 602
Tdark 4 | 7,003

IMPC Term

preweaning lethality, complete... 6 | 633
decreased body weight 3 | 174
decreased bone mineral density 3 | 126
decreased grip strength 3 | 123
abnormal behavior 2 | 226
abnormal testis morphology 2 | 30
decreased bone mineral content 2 | 157
decreased circulating insulin ... 2 | 75
decreased circulating triglyce... 2 | 83
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
hypoactivity 2 | 89
increased mean corpuscular hem... 2 | 93
increased total body fat amoun... 2 | 57
male infertility 2 | 62
preweaning lethality, incomple... 2 | 260
small testis 2 | 37
thrombocytopenia 2 | 46
abnormal body wall morphology 1 | 7
abnormal cervical vertebrae mo... 1 | 4
abnormal coat/ hair morphology 1 | 18
abnormal coat/hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal eye morphology 1 | 38
abnormal facial morphology 1 | 9
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal humerus morphology 1 | 11
abnormal lens morphology 1 | 73
abnormal limb bud morphology 1 | 15
abnormal limb morphology 1 | 7
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal inner nuclear... 1 | 5
abnormal rib morphology 1 | 28
abnormal spleen morphology 1 | 36
abnormal tail morphology 1 | 17
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cataract 1 | 26
cleft palate 1 | 6
decreased body length 1 | 108
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased food intake 1 | 6
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased red blood cell distr... 1 | 11
decreased spleen weight 1 | 13
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
embryonic growth retardation 1 | 28
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged heart 1 | 111
enlarged liver 1 | 3
enlarged spleen 1 | 26
female infertility 1 | 34
hemorrhage 1 | 12
hydrometra 1 | 13
increased aggression 1 | 2
increased blood urea nitrogen ... 1 | 44
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating alkaline... 1 | 119
increased circulating aspartat... 1 | 17
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 91
increased spleen weight 1 | 3
lethargy 1 | 5
limb grasping 1 | 35
premature death 1 | 5
prenatal lethality prior to he... 1 | 64
small seminal vesicle 1 | 6
small superior vagus ganglion 1 | 20
straub tail 1 | 26
tremors 1 | 34

Disease

Kidney Diseases 86 | 86
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 86 | 18,473
Endocrine System 85 | 18,512
Female tissues 85 | 18,647
Liver and Pancreas 85 | 18,136
Nervous System 85 | 18,561
Skin and soft tissues 85 | 18,115
Urinary Tract 85 | 18,444
Cardiovascular System 84 | 17,958
Blood and immune system 83 | 17,995
Male tissues 83 | 17,969
Respiratory system 79 | 17,484

Target Family

Non-IDG 44 | 11,969
Enzyme 23 | 4,146
Transcription Factor 7 | 1,400
Transporter 4 | 473
GPCR 3 | 408
Kinase 3 | 634
Ion Channel 1 | 341
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pro-opiomelanocortin POMC Tbio Non-IDG -4.55455 36028.8 1100
Atypical chemokine receptor 3 ACKR3 Tchem GPCR -1.80879 81.4 385
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.66762 4846.8 245
Probable tRNA(His) guanylyltransferase THG1L Tbio Enzyme -0.47712 3.69 62
Tubulointerstitial nephritis antigen TINAG Tdark Non-IDG -1.39157 26.9 49
Calbindin CALB1 Tbio Non-IDG -3.30395 2070.6 233
Angiotensinogen AGT Tchem Non-IDG -3.23867 1673.4 609
Cystatin-C CST3 Tbio Non-IDG -3.48935 3020.7 756
Interleukin-33 IL33 Tbio Non-IDG -2.78393 721.2 618
Intraflagellar transport protein 122 homolog IFT122 Tdark Non-IDG -1.49089 28.9 47