Development Level

Tbio 57 | 10,625
Tchem 17 | 1,890
Tdark 7 | 7,003
Tclin 6 | 602

IMPC Term

increased mean corpuscular hem... 4 | 93
decreased bone mineral density 3 | 126
increased circulating serum al... 3 | 25
abnormal bone mineralization 2 | 55
abnormal bone structure 2 | 131
decreased CD4-positive, CD25-p... 2 | 24
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased gamma-delta T cell n... 2 | 18
decreased lean body mass 2 | 195
decreased neutrophil cell numb... 2 | 37
decreased rib number 2 | 59
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased effector memory CD4-... 2 | 15
increased hemoglobin content 2 | 45
increased neutrophil cell numb... 2 | 15
abnormal behavior 1 | 226
abnormal behavioral response t... 1 | 52
abnormal coping response 1 | 12
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal thoracic cage shape 1 | 3
decreased B cell number 1 | 30
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased CD8-positive, naive ... 1 | 5
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased body length 1 | 108
decreased circulating creatini... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased effector memory CD8-... 1 | 24
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased lumbar vertebrae num... 1 | 62
decreased lymphocyte cell numb... 1 | 9
decreased mature B cell number 1 | 25
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged heart 1 | 111
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased KLRG1+ CD8 alpha bet... 1 | 2
increased KLRG1-positive CD4-n... 1 | 1
increased KLRG1-positive CD4-p... 1 | 3
increased KLRG1-positive NK ce... 1 | 9
increased KLRG1-positive T-hel... 1 | 2
increased KLRG1-positive gamma... 1 | 2
increased Ly6C low monocyte nu... 1 | 8
increased NK cell number 1 | 19
increased body length 1 | 20
increased caudal vertebrae num... 1 | 8
increased circulating calcium ... 1 | 32
increased circulating free fat... 1 | 17
increased effector memory CD8-... 1 | 14
increased effector memory T-he... 1 | 5
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased memory CD4-positive,... 1 | 3
increased memory-marker CD4-ne... 1 | 1
increased monocyte cell number 1 | 27
increased myeloid cell number 1 | 2
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
kinked tail 1 | 3
prenatal lethality prior to he... 1 | 64
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
small superior vagus ganglion 1 | 20
vertebral transformation 1 | 12

Disease

Inflammatory Bowel Diseases 87 | 87
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 86 | 18,473
Female tissues 86 | 18,647
Liver and Pancreas 86 | 18,136
Skin and soft tissues 86 | 18,115
Urinary Tract 86 | 18,444
Blood and immune system 85 | 17,995
Cardiovascular System 85 | 17,958
Nervous System 85 | 18,561
Respiratory system 85 | 17,484
Endocrine System 84 | 18,512
Male tissues 84 | 17,969

Target Family

Non-IDG 49 | 11,971
Enzyme 17 | 4,146
Transcription Factor 8 | 1,400
GPCR 4 | 406
Epigenetic 3 | 242
Kinase 3 | 634
Transporter 2 | 473
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 22 member 4 SLC22A4 Tchem Transporter -3.04092 1151.9 69
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648
Inositol polyphosphate multikinase IPMK Tbio Kinase -1.49619 35.9 131
Low affinity immunoglobulin gamma Fc region receptor II-a FCGR2A Tbio Non-IDG -2.87960 775.0 717
Hepatocyte growth factor-like protein MST1 Tbio Enzyme -2.02220 90.5 0
Mothers against decapentaplegic homolog 3 SMAD3 Tbio Transcription Factor -3.03840 1043.2 1391
Tetraspanin-14 TSPAN14 Tdark Non-IDG -0.11344 1.08 33
Beta-defensin 4A DEFB4A Tbio Non-IDG -2.68546 87.1 124
Psychosine receptor GPR65 Tbio GPCR -1.43622 31.9 163
Zinc finger protein 831 ZNF831 Tdark Transcription Factor 0.00000 5