Development Level

Tbio 14 | 11,445
Tclin 9 | 613
Tchem 5 | 1,598

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

decreased bone mineral content 3 | 151
decreased lean body mass 3 | 135
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
increased circulating creatini... 3 | 38
increased total body fat amoun... 3 | 134
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased bone mineral density 2 | 126
decreased circulating chloride... 2 | 30
decreased heart weight 2 | 27
decreased lymphocyte cell numb... 2 | 83
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
increased circulating phosphat... 2 | 26
increased circulating serum al... 2 | 22
increased circulating total pr... 2 | 28
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 92
limb grasping 2 | 41
abnormal bone structure 1 | 187
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal gait 1 | 69
abnormal locomotor behavior 1 | 24
abnormal male genitalia morpho... 1 | 3
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
embryonic lethality prior to o... 1 | 239
enlarged liver 1 | 2
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
oligodactyly 1 | 1
polydactyly 1 | 7
small kidney 1 | 16
small seminal vesicle 1 | 10
small testis 1 | 58
thin ventricular wall 1 | 24
thrombocytopenia 1 | 56
tremors 1 | 39
trunk curl 1 | 16

Disease

Infertility, Female 28 | 28
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 27 | 17,369
Endocrine System 27 | 18,159
Female tissues 27 | 17,400
Liver and Pancreas 27 | 16,750
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Male tissues 26 | 17,142
Respiratory system 26 | 16,393
Urinary Tract 26 | 16,678
Nervous System 25 | 16,725
Cardiovascular System 23 | 15,192

Target Family

Non-IDG 10 | 12,091
Nuclear Receptor 6 | 48
Enzyme 4 | 4,145
Transcription Factor 4 | 1,400
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
Leukemia inhibitory factor LIF Tbio Non-IDG -2.86943 538.7 413
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
Dihydrofolate reductase DHFR Tclin Enzyme -2.99192 972.8 202
CCAAT/enhancer-binding protein alpha CEBPA Tbio Transcription Factor -2.94393 846.3 518
Nuclear receptor subfamily 1 group I member 2 NR1I2 Tchem Nuclear Receptor -3.15331 1582.6 305
Estrogen receptor beta ESR2 Tclin Nuclear Receptor -3.57388 3765.2 1096
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369