Development Level

Tbio 103 | 10,625
Tdark 25 | 7,003
Tchem 18 | 1,890
Tclin 17 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

decreased bone mineral content 5 | 157
decreased bone mineral density 4 | 126
decreased lean body mass 4 | 195
abnormal behavior 3 | 226
hypoactivity 3 | 89
increased circulating alkaline... 3 | 119
increased total body fat amoun... 3 | 57
male infertility 3 | 62
abnormal bone structure 2 | 131
abnormal ovary morphology 2 | 3
abnormal seminal vesicle morph... 2 | 47
decreased body weight 2 | 174
female infertility 2 | 34
increased circulating HDL chol... 2 | 63
increased circulating calcium ... 2 | 32
increased circulating choleste... 2 | 53
increased circulating serum al... 2 | 25
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
small kidney 2 | 10
abnormal behavioral response t... 1 | 52
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal kidney morphology 1 | 30
abnormal lens morphology 1 | 73
abnormal liver morphology 1 | 5
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal optic disc morphology 1 | 10
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal thymus morphology 1 | 1
absent epididymis 1 | 2
absent ovary 1 | 2
absent seminal vesicle 1 | 2
absent testes 1 | 2
absent uterus 1 | 1
decreased IgE level 1 | 3
decreased brain size 1 | 4
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating chloride... 1 | 32
decreased circulating fructosa... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased heart weight 1 | 44
decreased lactate dehydrogenas... 1 | 14
decreased leukocyte cell numbe... 1 | 54
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
enlarged heart 1 | 111
enlarged liver 1 | 3
enlarged thymus 1 | 4
fusion of vertebral arches 1 | 7
improved glucose tolerance 1 | 56
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
lethargy 1 | 5
no abnormal phenotype detected 1 | 3
polysyndactyly 1 | 2
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
shortened PQ interval 1 | 6
shortened PR interval 1 | 5
small heart 1 | 8
small liver 1 | 8
small lung 1 | 5
small seminal vesicle 1 | 6
small spleen 1 | 11
small stomach 1 | 3
small superior vagus ganglion 1 | 20
small testis 1 | 37
small thymus 1 | 11
thrombocytopenia 1 | 46
tremors 1 | 34
urinary bladder obstruction 1 | 2
vertebral transformation 1 | 12

Disease

Infertility 163 | 163
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Endocrine System 159 | 18,512
Female tissues 158 | 18,647
Digestive Tract 155 | 18,473
Nervous System 154 | 18,561
Urinary Tract 153 | 18,444
Liver and Pancreas 151 | 18,136
Male tissues 150 | 17,969
Skin and soft tissues 149 | 18,115
Cardiovascular System 144 | 17,958
Blood and immune system 142 | 17,995
Respiratory system 131 | 17,484

Target Family

Non-IDG 96 | 11,971
Enzyme 27 | 4,146
Transcription Factor 15 | 1,400
GPCR 6 | 406
Nuclear Receptor 6 | 48
Epigenetic 4 | 242
Kinase 4 | 634
Ion Channel 3 | 341
oGPCR 2 | 421

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.34520 2413.2 212
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Kelch-like protein 10 KLHL10 Tdark Non-IDG -0.62839 4.48 35
Putative methyltransferase NSUN7 NSUN7 Tdark Enzyme -0.64137 4.34 10
Structural maintenance of chromosomes protein 1B SMC1B Tbio Non-IDG -1.26509 19.6 93
Cleavage stimulation factor subunit 2 tau variant CSTF2T Tbio Non-IDG -0.86156 8.94 118
Forkhead box protein L2 FOXL2 Tbio Transcription Factor -2.76212 610.7 220
Nanos homolog 3 NANOS3 Tbio Non-IDG -1.55057 39.4 76
Nanos homolog 2 NANOS2 Tbio Non-IDG -1.47621 32.1 173