Development Level

Tbio 139 | 11,651
Tchem 19 | 1,388
Tclin 17 | 612
Tdark 1 | 6,593

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 30 | 979
abnormal embryo size 7 | 220
embryonic lethality prior to o... 7 | 239
embryonic lethality prior to t... 7 | 278
impaired glucose tolerance 6 | 75
decreased body weight 5 | 161
decreased lean body mass 5 | 135
cataract 4 | 92
decreased bone mineral content 4 | 151
embryonic growth retardation 4 | 106
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
abnormal seminal vesicle morph... 3 | 114
increased grip strength 3 | 41
increased total body fat amoun... 3 | 134
prenatal lethality prior to he... 3 | 87
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal joint morphology 2 | 23
abnormal pericardium morpholog... 2 | 26
abnormal retina morphology 2 | 71
brachydactyly 2 | 19
decreased bone mineral density 2 | 126
decreased fasted circulating g... 2 | 65
decreased heart left ventricle... 2 | 28
decreased neutrophil cell numb... 2 | 42
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
edema 2 | 59
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased startle reflex 2 | 112
limb grasping 2 | 41
male infertility 2 | 123
pale yolk sac 2 | 25
syndactyly 2 | 23
abnormal bone structure 1 | 187
abnormal brain morphology 1 | 13
abnormal coat- hair morphology 1 | 19
abnormal coat-hair pigmentatio... 1 | 64
abnormal craniofacial morpholo... 1 | 33
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal iris morphology 1 | 13
abnormal liver morphology 1 | 17
abnormal neural tube closure 1 | 46
abnormal snout morphology 1 | 23
abnormal spinal cord morpholog... 1 | 9
abnormal spine curvature 1 | 9
abnormal stomach morphology 1 | 10
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
decreased B cell number 1 | 5
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
excessive tearing 1 | 2
eyelids fail to open 1 | 3
female infertility 1 | 60
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
increased aggression 1 | 4
increased circulating HDL chol... 1 | 80
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
pallor 1 | 34
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
prolonged ST segment 1 | 36
small adrenal glands 1 | 16
thin ventricular wall 1 | 24

Disease

Infant, Small for Gestational Age 176 | 176
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 173 | 17,369
Endocrine System 173 | 18,159
Skin and soft tissues 170 | 17,230
Blood and immune system 169 | 16,909
Female tissues 169 | 17,400
Male tissues 169 | 17,142
Liver and Pancreas 166 | 16,750
Respiratory system 166 | 16,393
Urinary Tract 166 | 16,678
Nervous System 165 | 16,725
Cardiovascular System 163 | 15,192

Target Family

Non-IDG 83 | 12,091
Enzyme 47 | 4,145
Transcription Factor 19 | 1,400
Kinase 15 | 634
Epigenetic 4 | 242
Ion Channel 4 | 344
Transporter 3 | 473
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Meckel syndrome type 1 protein MKS1 Tbio Non-IDG -1.31837 20.5 59
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Poly(A)-specific ribonuclease PARN PARN Tbio Enzyme -1.87605 76.4 263
Telomerase Cajal body protein 1 WRAP53 Tbio Enzyme -1.50893 31.5 58
Transmembrane protein 70, mitochondrial TMEM70 Tbio Non-IDG -1.36229 24.6 93
Cbp/p300-interacting transactivator 2 CITED2 Tbio Non-IDG -2.07760 134.8 167
Phosphoserine aminotransferase PSAT1 Tbio Enzyme -2.25926 176.4 136
Origin recognition complex subunit 6 ORC6 Tbio Non-IDG -1.38268 26.3 165
V-type proton ATPase 116 kDa subunit a isoform 2 ATP6V0A2 Tbio Enzyme -2.46402 298.9 76
Cell division control protein 6 homolog CDC6 Tbio Non-IDG -2.51683 336.8 574