Development Level

Tbio 115 | 11,445
Tchem 20 | 1,598
Tclin 12 | 613

IMPC Phenotype

preweaning lethality, complete... 17 | 979
decreased body weight 5 | 161
abnormal behavior 4 | 298
abnormal embryo size 4 | 220
decreased total body fat amoun... 4 | 207
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
abnormal eye morphology 3 | 68
abnormal retinal blood vessel ... 3 | 26
abnormal retinal vasculature m... 3 | 27
abnormal stomach morphology 3 | 10
decreased bone mineral content 3 | 151
decreased grip strength 3 | 116
decreased mean corpuscular vol... 3 | 79
embryonic lethality prior to o... 3 | 239
impaired glucose tolerance 3 | 75
increased fasted circulating g... 3 | 76
increased mean corpuscular hem... 3 | 96
increased total body fat amoun... 3 | 134
male infertility 3 | 123
abnormal cornea morphology 2 | 31
abnormal gait 2 | 69
abnormal retina morphology 2 | 71
abnormal tail morphology 2 | 25
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased lean body mass 2 | 135
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
female infertility 2 | 60
increased body weight 2 | 25
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
increased mean corpuscular vol... 2 | 92
short tibia 2 | 97
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal head shape 1 | 10
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal limb bud morphology 1 | 17
abnormal liver morphology 1 | 17
abnormal liver size 1 | 5
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
cleft palate 1 | 8
corneal opacity 1 | 32
decreased IgG1 level 1 | 8
decreased body length 1 | 101
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased heart left ventricle... 1 | 28
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular hem... 1 | 31
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
limb grasping 1 | 41
pale liver 1 | 6
pale yolk sac 1 | 25
pallor 1 | 34
protruding tongue 1 | 3
thin ventricular wall 1 | 24
unresponsive to tactile stimul... 1 | 8

Disease

Increased size of cranium 147 | 147
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 147 | 18,159
Female tissues 147 | 17,400
Male tissues 147 | 17,142
Skin and soft tissues 147 | 17,230
Urinary Tract 147 | 16,678
Digestive Tract 146 | 17,369
Liver and Pancreas 146 | 16,750
Nervous System 145 | 16,725
Respiratory system 144 | 16,393
Blood and immune system 143 | 16,909
Cardiovascular System 139 | 15,192

Target Family

Non-IDG 69 | 12,091
Enzyme 40 | 4,145
Kinase 11 | 634
Transcription Factor 11 | 1,400
Epigenetic 7 | 242
Ion Channel 4 | 344
Transporter 4 | 473
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Peroxisome biogenesis factor 2 PEX2 Tbio Non-IDG -1.76849 57.3 170
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
Sorting nexin-10 SNX10 Tbio Non-IDG -1.13183 16.8 72
Adenomatous polyposis coli protein 2 APC2 Tbio Non-IDG -1.50271 33.3 93
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Protein patched homolog 2 PTCH2 Tbio Non-IDG -1.80541 50.4 92
Peroxisome assembly factor 2 PEX6 Tbio Enzyme -1.89379 79.8 148
Lysine-specific demethylase 5C KDM5C Tchem TF/Epigenetic -1.94004 86.4 135
Translation initiation factor eIF-2B subunit delta EIF2B4 Tbio Non-IDG -1.06082 11.3 145
Palmitoyltransferase ZDHHC9 ZDHHC9 Tbio Enzyme -1.12039 12.7 144