Development Level

Tbio 19 | 11,445
Tclin 11 | 613
Tchem 10 | 1,598
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal locomotor activation 1 | 16
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased circulating phosphat... 1 | 27
decreased hematocrit 1 | 46
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
preweaning lethality, complete... 1 | 979
prolonged ST segment 1 | 36
small testis 1 | 58

Disease

Impotence 42 | 42
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 42 | 17,369
Endocrine System 42 | 18,159
Female tissues 41 | 17,400
Liver and Pancreas 41 | 16,750
Urinary Tract 41 | 16,678
Blood and immune system 40 | 16,909
Male tissues 40 | 17,142
Skin and soft tissues 40 | 17,230
Respiratory system 39 | 16,393
Nervous System 38 | 16,725
Cardiovascular System 36 | 15,192

Target Family

Non-IDG 17 | 12,091
Enzyme 15 | 4,145
Kinase 5 | 634
GPCR 2 | 408
Ion Channel 1 | 344
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A Tchem Enzyme -1.53120 38.8 218
Y-box-binding protein 2 YBX2 Tbio Transcription Factor -1.99119 94.8 236
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A PDE9A Tchem Enzyme -1.92564 78.9 151
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.35296 2270.4 122
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.14670 1303.9 150
Actin-binding protein IPP IPP Tdark Non-IDG -2.93193 840.1 31
cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A Tclin Enzyme -3.07830 1256.9 314
Calcium-activated potassium channel subunit alpha-1 KCNMA1 Tclin Ion Channel -3.09649 1238.5 222