Development Level

Tbio 291 | 10,625
Tchem 100 | 1,890
Tdark 44 | 7,003
Tclin 19 | 602

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, complete... 24 | 633
embryonic lethality prior to t... 10 | 187
preweaning lethality, incomple... 10 | 260
embryonic lethality prior to o... 7 | 148
increased mean corpuscular hem... 7 | 93
abnormal behavior 6 | 226
decreased body weight 5 | 174
enlarged heart 5 | 111
short tibia 5 | 82
abnormal heart morphology 4 | 51
abnormal retina morphology 4 | 100
abnormal sleep behavior 4 | 63
decreased circulating glucose ... 4 | 121
decreased grip strength 4 | 123
decreased hemoglobin content 4 | 53
decreased mean corpuscular vol... 4 | 50
decreased total body fat amoun... 4 | 186
hypoactivity 4 | 89
increased circulating alkaline... 4 | 119
increased mean corpuscular hem... 4 | 25
increased mean corpuscular vol... 4 | 91
abnormal embryo size 3 | 112
abnormal skin morphology 3 | 23
decreased circulating HDL chol... 3 | 77
decreased circulating calcium ... 3 | 33
decreased mean corpuscular hem... 3 | 34
hydrops fetalis 3 | 22
increased grip strength 3 | 83
increased hemoglobin content 3 | 45
thrombocytopenia 3 | 46
tremors 3 | 34
abnormal bone structure 2 | 131
abnormal coat/hair pigmentatio... 2 | 54
abnormal epididymis morphology 2 | 31
abnormal femur morphology 2 | 14
abnormal kidney morphology 2 | 30
abnormal lens morphology 2 | 73
abnormal limb bud morphology 2 | 15
abnormal neural tube closure 2 | 37
abnormal neural tube morpholog... 2 | 8
abnormal retinal pigmentation 2 | 61
abnormal spleen morphology 2 | 36
abnormal tail morphology 2 | 17
cardiovascular system phenotyp... 2 | 35
decreased basophil cell number 2 | 11
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 49
decreased circulating alkaline... 2 | 41
decreased circulating choleste... 2 | 85
decreased circulating free fat... 2 | 39
decreased circulating serum al... 2 | 79
decreased effector memory CD8-... 2 | 24
decreased erythrocyte cell num... 2 | 43
decreased fasted circulating g... 2 | 49
decreased heart weight 2 | 44
decreased hematocrit 2 | 25
decreased lean body mass 2 | 195
decreased mean corpuscular hem... 2 | 19
decreased monocyte cell number 2 | 28
enlarged epididymis 2 | 27
hyperactivity 2 | 108
improved glucose tolerance 2 | 56
increased body length 2 | 20
increased bone mineral content 2 | 92
increased circulating HDL chol... 2 | 63
increased circulating calcium ... 2 | 32
increased circulating choleste... 2 | 53
increased circulating glucose ... 2 | 16
increased circulating phosphat... 2 | 24
increased circulating sodium l... 2 | 71
increased hematocrit 2 | 36
increased leukocyte cell numbe... 2 | 37
increased or absent threshold ... 2 | 128
increased prepulse inhibition 2 | 21
increased spleen weight 2 | 3
long tibia 2 | 13
male infertility 2 | 62
pale yolk sac 2 | 12
straub tail 2 | 26
thick ventricular wall 2 | 7
abnormal behavioral response t... 1 | 52
abnormal cranium morphology 1 | 32
abnormal tooth morphology 1 | 24
corneal opacity 1 | 25
decreased Ly6C high monocyte n... 1 | 18
decreased blood urea nitrogen ... 1 | 31
decreased circulating chloride... 1 | 32
decreased circulating magnesiu... 1 | 11
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased neutrophil cell numb... 1 | 37
enlarged spleen 1 | 26
increased NK cell number 1 | 19
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating triglyce... 1 | 24
increased sacral vertebrae num... 1 | 62
limb grasping 1 | 35

Disease

IGA Glomerulonephritis 454 | 454
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Blood and immune system 452 | 17,995
Digestive Tract 452 | 18,473
Female tissues 452 | 18,647
Liver and Pancreas 452 | 18,136
Male tissues 452 | 17,969
Endocrine System 451 | 18,512
Nervous System 451 | 18,561
Respiratory system 450 | 17,484
Urinary Tract 450 | 18,444
Cardiovascular System 449 | 17,958
Skin and soft tissues 445 | 18,115

Target Family

Non-IDG 268 | 11,971
Enzyme 119 | 4,146
Kinase 28 | 634
Transporter 14 | 473
Transcription Factor 13 | 1,400
GPCR 8 | 406
Epigenetic 3 | 242
Ion Channel 1 | 341

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
G2/mitotic-specific cyclin-B1 CCNB1 Tchem Non-IDG -3.09727 1121.4 955
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Charged multivesicular body protein 2b CHMP2B Tbio Non-IDG -1.65708 53.0 166
Proliferating cell nuclear antigen PCNA Tchem Non-IDG -1.10426 11.5 1277
Desmoplakin DSP Tbio Non-IDG -2.90088 786.5 167
Apolipoprotein C-I APOC1 Tbio Non-IDG -2.37678 252.9 236
Macrophage metalloelastase MMP12 Tchem Enzyme 0.00000 382
Actin-related protein 2 ACTR2 Tchem Non-IDG -1.84526 72.5 184
Centromere protein F CENPF Tbio Non-IDG -1.98596 103.0 180