Development Level

Tbio 31 | 11,178
Tclin 6 | 612
Tdark 6 | 6,569
Tchem 5 | 1,885

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased lean body mass 4 | 135
increased circulating alkaline... 4 | 122
abnormal behavior 3 | 298
increased total body fat amoun... 3 | 134
abnormal craniofacial morpholo... 2 | 33
abnormal male genitalia morpho... 2 | 3
decreased bone mineral content 2 | 151
decreased respiratory quotient 2 | 16
embryonic lethality prior to t... 2 | 278
improved glucose tolerance 2 | 79
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
polydactyly 2 | 7
preweaning lethality, incomple... 2 | 499
abnormal QT variability 1 | 10
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal eyelid fusion 1 | 3
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin appearance 1 | 3
abnormal skin coloration 1 | 25
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
cataract 1 | 92
corneal opacity 1 | 32
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
decreased cardiac stroke volum... 1 | 6
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating phosphat... 1 | 27
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased prepulse inhibition 1 | 82
edema 1 | 59
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
fused cornea and lens 1 | 5
fusion of vertebral arches 1 | 7
hemorrhage 1 | 23
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
iris synechia 1 | 3
limb grasping 1 | 41
long tibia 1 | 25
male infertility 1 | 123
narrow eye opening 1 | 12
oligodactyly 1 | 1
persistence of hyaloid vascula... 1 | 33
polysyndactyly 1 | 2
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
prolonged RR interval 1 | 8
shortened QT interval 1 | 4
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small superior vagus ganglion 1 | 74
small thymus 1 | 16
vertebral transformation 1 | 12

Disease

Hypospadias 48 | 48
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 48 | 18,159
Skin and soft tissues 45 | 17,230
Digestive Tract 44 | 17,369
Female tissues 44 | 17,400
Male tissues 44 | 17,142
Nervous System 43 | 16,725
Urinary Tract 42 | 16,678
Liver and Pancreas 40 | 16,750
Blood and immune system 39 | 16,909
Respiratory system 39 | 16,393
Cardiovascular System 33 | 15,192

Target Family

Transcription Factor 18 | 1,400
Enzyme 13 | 4,145
Non-IDG 13 | 12,091
Nuclear Receptor 2 | 48
GPCR 1 | 408
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Wilms tumor protein WT1 Tbio Transcription Factor -3.48344 3138.9 571
Zinc finger E-box-binding homeobox 2 ZEB2 Tbio Transcription Factor -2.49656 262.6 474
Zinc finger protein 30 ZNF30 Tdark Transcription Factor 0.28 0.32 70
Probable ATP-dependent RNA helicase DHX34 DHX34 Tbio Enzyme -0.34321 2.61 39
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369
Protein ERGIC-53-like LMAN1L Tbio Non-IDG -0.42233 2.28 79
Homeobox protein Hox-A13 HOXA13 Tbio Transcription Factor -2.00063 103.6 114
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 HSD3B1 Tchem Enzyme -2.62147 370.7 267
Wilms tumor protein 1-interacting protein WTIP Tbio Non-IDG -1.82042 59.4 59
Homeobox protein Hox-A4 HOXA4 Tbio Transcription Factor -1.55139 36.0 132