Development Level

Tbio 42 | 10,625
Tdark 9 | 7,003
Tchem 7 | 1,890
Tclin 7 | 602

IMPC Term

preweaning lethality, complete... 4 | 633
decreased bone mineral content 3 | 157
decreased lean body mass 3 | 195
abnormal behavior 2 | 226
embryonic lethality prior to t... 2 | 187
increased circulating HDL chol... 2 | 63
increased circulating serum al... 2 | 25
increased total body fat amoun... 2 | 57
preweaning lethality, incomple... 2 | 260
abnormal behavioral response t... 1 | 52
abnormal bone structure 1 | 131
abnormal cornea morphology 1 | 24
abnormal craniofacial morpholo... 1 | 12
abnormal embryo size 1 | 112
abnormal forebrain morphology 1 | 4
abnormal hindbrain morphology 1 | 2
abnormal midbrain morphology 1 | 2
abnormal neural tube closure 1 | 37
abnormal pericardium morpholog... 1 | 11
abnormal retinal pigmentation 1 | 61
abnormal seminal vesicle morph... 1 | 47
corneal opacity 1 | 25
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased kidney weight 1 | 7
decreased spleen weight 1 | 13
edema 1 | 11
enlarged heart 1 | 111
fusion of vertebral arches 1 | 7
hemorrhage 1 | 12
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased fasted circulating g... 1 | 68
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
increased monocyte cell number 1 | 27
increased or absent threshold ... 1 | 128
limb grasping 1 | 35
narrow eye opening 1 | 15
no abnormal phenotype detected 1 | 3
polysyndactyly 1 | 2
prenatal lethality 1 | 16
shortened QT interval 1 | 4
small heart 1 | 8
small kidney 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small stomach 1 | 3
small superior vagus ganglion 1 | 20
small thymus 1 | 11
trunk curl 1 | 15
vertebral transformation 1 | 12

Disease

Hypospadias 65 | 65
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Nervous System 65 | 18,561
Digestive Tract 64 | 18,473
Endocrine System 64 | 18,512
Female tissues 64 | 18,647
Liver and Pancreas 64 | 18,136
Cardiovascular System 63 | 17,958
Male tissues 63 | 17,969
Skin and soft tissues 63 | 18,115
Urinary Tract 63 | 18,444
Blood and immune system 62 | 17,995
Respiratory system 60 | 17,484

Target Family

Transcription Factor 24 | 1,400
Non-IDG 20 | 11,971
Enzyme 13 | 4,146
Nuclear Receptor 3 | 48
Kinase 2 | 634
GPCR 1 | 406
Ion Channel 1 | 341
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Muellerian-inhibiting factor AMH Tbio Non-IDG -3.34520 2413.2 212
Probable phospholipid-transporting ATPase IIB ATP9B Tdark Transporter -0.57248 3.74 5
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.51373 345.1 271
Zinc finger protein 541 ZNF541 Tdark Transcription Factor 0.85 0.14 80
Nuclear receptor subfamily 0 group B member 1 NR0B1 Tchem Nuclear Receptor -2.70036 522.8 435
Homeobox protein Hox-A2 HOXA2 Tbio Transcription Factor -2.27536 194.5 72
Homeobox protein Hox-A3 HOXA3 Tbio Transcription Factor -1.61940 43.1 146
Transcription factor HES-3 HES3 Tbio Transcription Factor -1.60948 41.8 28
DNA-binding protein SATB2 SATB2 Tbio Transcription Factor -2.81941 654.1 179
E3 ubiquitin-protein ligase TRIM17 TRIM17 Tbio Enzyme -1.90792 73.2 100