Development Level

Tbio 74 | 11,651
Tchem 9 | 1,388
Tclin 5 | 612
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, complete... 14 | 979
decreased body weight 6 | 161
embryonic lethality prior to o... 5 | 239
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
embryonic lethality prior to t... 4 | 278
abnormal bone mineralization 2 | 38
abnormal embryo size 2 | 220
abnormal retina morphology 2 | 71
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased heart rate 2 | 18
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased startle reflex 2 | 112
increased total body fat amoun... 2 | 134
mammalian phenotype 2 | 17
abnormal bone structure 1 | 187
abnormal embryo development 1 | 7
abnormal esophagus morphology 1 | 5
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal pancreas morphology 1 | 13
abnormal response to new envir... 1 | 10
abnormal skin coloration 1 | 25
abnormal startle reflex 1 | 15
abnormal thyroid gland morphol... 1 | 3
abnormal trachea morphology 1 | 3
abnormal vitreous body morphol... 1 | 10
absent adrenal gland 1 | 2
absent lymph nodes 1 | 3
absent startle reflex 1 | 24
anophthalmia 1 | 33
cataract 1 | 92
decreased IgM level 1 | 1
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased fasted circulating g... 1 | 65
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
enlarged lymph nodes 1 | 37
enlarged thymus 1 | 5
enlarged urinary bladder 1 | 8
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating amylase ... 1 | 25
increased circulating creatini... 1 | 38
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
limb grasping 1 | 41
premature death 1 | 5
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
prolonged RR interval 1 | 8

Disease

Hypoplasia of corpus callosum 90 | 90
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 89 | 18,159
Blood and immune system 88 | 16,909
Digestive Tract 88 | 17,369
Nervous System 88 | 16,725
Cardiovascular System 87 | 15,192
Female tissues 87 | 17,400
Liver and Pancreas 87 | 16,750
Male tissues 87 | 17,142
Respiratory system 87 | 16,393
Skin and soft tissues 87 | 17,230
Urinary Tract 87 | 16,678

Target Family

Non-IDG 41 | 12,091
Enzyme 34 | 4,145
Transcription Factor 8 | 1,400
Kinase 4 | 634
Transporter 3 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Homeobox protein SIX6 SIX6 Tbio Transcription Factor -2.23077 163.2 112
Protein O-mannosyl-transferase 2 POMT2 Tbio Enzyme -1.48456 31.6 104
Mannosyl-oligosaccharide glucosidase MOGS Tbio Enzyme -2.28289 185.6 149
AP-4 complex subunit beta-1 AP4B1 Tbio Non-IDG -0.79214 6.23 124
Immediate early response 3-interacting protein 1 IER3IP1 Tbio Non-IDG -2.47342 292.3 18
F-box/LRR-repeat protein 4 FBXL4 Tbio Non-IDG -1.13805 13.4 82
Tubulin beta-3 chain TUBB3 Tclin Non-IDG -2.08746 87.9 594
Phospholipase DDHD2 DDHD2 Tbio Enzyme -1.23833 16.6 49
Bifunctional polynucleotide phosphatase/kinase PNKP Tbio Enzyme -1.79273 59.8 231
AT-hook DNA-binding motif-containing protein 1 AHDC1 Tdark Non-IDG -0.69567 3.70 14