Development Level

Tbio 39 | 10,625
Tchem 28 | 1,890
Tclin 12 | 602
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 3 | 260
decreased bone mineral content 2 | 157
decreased fasted circulating g... 2 | 49
enlarged heart 2 | 111
increased circulating sodium l... 2 | 71
abnormal bone structure 1 | 131
abnormal coat/hair pigmentatio... 1 | 54
abnormal epididymis morphology 1 | 31
abnormal heart left ventricle ... 1 | 20
abnormal lung morphology 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal urinary bladder morph... 1 | 2
abnormal vertebrae morphology 1 | 14
abnormal vibrissa morphology 1 | 17
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alkaline... 1 | 41
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
enlarged epididymis 1 | 27
impaired glucose tolerance 1 | 52
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating phosphat... 1 | 24
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased exploration in new e... 1 | 56
increased or absent threshold ... 1 | 128
long tibia 1 | 13
short tibia 1 | 82

Disease

Hypoglycemia 81 | 81
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 81 | 18,473
Endocrine System 81 | 18,512
Female tissues 81 | 18,647
Nervous System 81 | 18,561
Skin and soft tissues 81 | 18,115
Liver and Pancreas 80 | 18,136
Urinary Tract 79 | 18,444
Blood and immune system 77 | 17,995
Cardiovascular System 77 | 17,958
Male tissues 73 | 17,969
Respiratory system 72 | 17,484

Target Family

Non-IDG 36 | 11,971
Enzyme 20 | 4,146
Transporter 13 | 473
GPCR 3 | 406
Transcription Factor 3 | 1,400
Ion Channel 2 | 341
Kinase 2 | 634
Nuclear Receptor 2 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.30074 2066.8 474
Trifunctional enzyme subunit alpha, mitochondrial HADHA Tbio Non-IDG -2.96515 948.2 132
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Protein Mis18-alpha MIS18A Tdark Non-IDG -2.10690 101.0 41
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.30451 203.2 252
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM Tbio Enzyme -2.58670 387.0 269
Glutamate dehydrogenase 1, mitochondrial GLUD1 Tbio Enzyme -2.36170 245.3 134