Development Level

Tbio 162 | 11,178
Tchem 57 | 1,885
Tclin 24 | 612
Tdark 2 | 6,569

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal heart morphology 5 | 162
decreased vertical activity 5 | 208
embryonic lethality prior to o... 5 | 239
embryonic lethality prior to t... 5 | 278
enlarged heart 5 | 210
increased lymphocyte cell numb... 4 | 32
increased neutrophil cell numb... 4 | 46
preweaning lethality, incomple... 4 | 499
small superior vagus ganglion 4 | 74
abnormal seminal vesicle morph... 3 | 114
decreased circulating creatini... 3 | 39
decreased mean corpuscular vol... 3 | 79
increased bone mineral density 3 | 72
abnormal bone structure 2 | 187
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
abnormal spleen morphology 2 | 55
decreased heart weight 2 | 27
decreased lymphocyte cell numb... 2 | 83
enlarged lymph nodes 2 | 37
enlarged uterus 2 | 11
hydrometra 2 | 53
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased eosinophil cell numb... 2 | 11
increased leukocyte cell numbe... 2 | 47
abnormal QT variability 1 | 10
abnormal anxiety-related respo... 1 | 1
abnormal behavior 1 | 298
abnormal cecum morphology 1 | 7
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal pancreas morphology 1 | 13
abnormal retinal vasculature m... 1 | 27
abnormal social-conspecific in... 1 | 3
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
aorta dilation 1 | 3
cataract 1 | 92
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
enlarged testis 1 | 6
female infertility 1 | 60
hypoactivity 1 | 132
impaired righting response 1 | 26
increased basophil cell number 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased heart rate 1 | 23
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
male infertility 1 | 123
pale yolk sac 1 | 25
persistence of hyaloid vascula... 1 | 33
prolonged PR interval 1 | 15
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Hypersensitivity reaction type II disease 245 | 245
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Digestive Tract 182 | 17,369
Blood and immune system 180 | 16,909
Endocrine System 178 | 18,159
Skin and soft tissues 178 | 17,230
Urinary Tract 178 | 16,678
Male tissues 176 | 17,142
Liver and Pancreas 175 | 16,750
Female tissues 173 | 17,400
Respiratory system 171 | 16,393
Nervous System 167 | 16,725
Cardiovascular System 154 | 15,192

Target Family

Non-IDG 203 | 12,091
Enzyme 20 | 4,145
Transcription Factor 7 | 1,400
GPCR 5 | 408
Kinase 3 | 634
Epigenetic 2 | 242
TF/Epigenetic 2 | 38
Transporter 2 | 473
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-4 IL4 Tbio Non-IDG -3.98318 9219.0 1325
T-lymphocyte activation antigen CD80 CD80 Tclin Non-IDG -3.39216 2405.6 1323
HLA class I histocompatibility antigen, B-67 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 362
Tumor necrosis factor receptor superfamily member 1B TNFRSF1B Tchem Non-IDG -3.67481 4484.7 712
Plasminogen-like protein A PLGLA Tdark Non-IDG -3.96245 15129.1 0
Heat shock 70 kDa protein 4 HSPA4 Tbio Non-IDG -3.92672 8635.1 432
HLA class I histocompatibility antigen, B-59 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Melanocortin-2 receptor accessory protein MRAP Tbio Non-IDG -3.60469 4145.9 102
Aquaporin-4 AQP4 Tchem Non-IDG -3.33435 2159.1 358
HLA class II histocompatibility antigen, DRB1-16 beta chain HLA-DRB1 Tbio Non-IDG -2.84258 1665.5 489