Development Level

Tbio 184 | 11,651
Tchem 42 | 1,388
Tclin 25 | 612
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, complete... 8 | 979
decreased vertical activity 6 | 208
embryonic lethality prior to t... 6 | 278
abnormal heart morphology 5 | 162
embryonic lethality prior to o... 5 | 239
enlarged heart 5 | 210
abnormal seminal vesicle morph... 4 | 114
increased lymphocyte cell numb... 4 | 32
increased neutrophil cell numb... 4 | 46
preweaning lethality, incomple... 4 | 499
small superior vagus ganglion 4 | 74
decreased circulating creatini... 3 | 39
decreased mean corpuscular vol... 3 | 79
increased bone mineral density 3 | 72
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
abnormal spleen morphology 2 | 55
decreased heart weight 2 | 27
decreased lymphocyte cell numb... 2 | 83
embryonic growth retardation 2 | 106
enlarged lymph nodes 2 | 37
enlarged uterus 2 | 11
hydrometra 2 | 53
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased eosinophil cell numb... 2 | 11
increased leukocyte cell numbe... 2 | 47
abnormal QT variability 1 | 10
abnormal anxiety-related respo... 1 | 1
abnormal behavior 1 | 298
abnormal cecum morphology 1 | 7
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal pancreas morphology 1 | 13
abnormal retinal vasculature m... 1 | 27
abnormal social-conspecific in... 1 | 3
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
aorta dilation 1 | 3
cataract 1 | 92
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased cardiac muscle contr... 1 | 11
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased monocyte cell number 1 | 8
decreased neutrophil cell numb... 1 | 42
decreased respiratory quotient 1 | 16
decreased spleen weight 1 | 10
decreased threshold for audito... 1 | 26
enlarged cecum 1 | 5
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
enlarged testis 1 | 6
female infertility 1 | 60
hypoactivity 1 | 132
impaired righting response 1 | 26
increased basophil cell number 1 | 7
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased heart rate 1 | 23
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
male infertility 1 | 123
pale yolk sac 1 | 25
persistence of hyaloid vascula... 1 | 33
prolonged PR interval 1 | 15
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
thin ventricular wall 1 | 24
vertebral fusion 1 | 23

Disease

Hypersensitivity reaction type II disease 253 | 253
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Digestive Tract 189 | 17,369
Blood and immune system 187 | 16,909
Endocrine System 185 | 18,159
Skin and soft tissues 185 | 17,230
Urinary Tract 185 | 16,678
Male tissues 183 | 17,142
Liver and Pancreas 182 | 16,750
Female tissues 180 | 17,400
Respiratory system 178 | 16,393
Nervous System 175 | 16,725
Cardiovascular System 160 | 15,192

Target Family

Non-IDG 209 | 12,091
Enzyme 22 | 4,145
Transcription Factor 7 | 1,400
GPCR 5 | 408
Kinase 3 | 634
Epigenetic 2 | 242
TF/Epigenetic 2 | 38
Transporter 2 | 473
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-9 IL9 Tbio Non-IDG -2.50811 334.4 459
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
T-cell surface glycoprotein CD3 zeta chain CD247 Tbio Non-IDG -2.61157 386.3 882
Tumor necrosis factor receptor superfamily member 4 TNFRSF4 Tbio Non-IDG -2.60147 430.2 524
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075