Development Level

Tbio 91 | 11,651
Tchem 14 | 1,388
Tclin 5 | 612
Tdark 1 | 6,593

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased body weight 4 | 161
increased startle reflex 4 | 112
decreased grip strength 3 | 116
decreased mean corpuscular vol... 3 | 79
decreased total body fat amoun... 3 | 207
increased lean body mass 3 | 172
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
decreased circulating glucose ... 2 | 126
decreased prepulse inhibition 2 | 82
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged kidney 2 | 14
enlarged lymph nodes 2 | 37
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased heart weight 2 | 62
increased mean corpuscular vol... 2 | 92
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal hair growth 1 | 10
abnormal kidney morphology 1 | 65
abnormal liver morphology 1 | 17
abnormal locomotor behavior 1 | 24
abnormal maxilla morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal stomach morphology 1 | 10
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
decreased basophil cell number 1 | 16
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased hemoglobin content 1 | 68
dilated heart left ventricle 1 | 11
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased circulating free fat... 1 | 20
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
prolonged RR interval 1 | 8
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Hyperkyphosis 111 | 111
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 109 | 16,909
Digestive Tract 109 | 17,369
Endocrine System 109 | 18,159
Male tissues 108 | 17,142
Nervous System 108 | 16,725
Skin and soft tissues 108 | 17,230
Female tissues 107 | 17,400
Liver and Pancreas 107 | 16,750
Respiratory system 106 | 16,393
Urinary Tract 106 | 16,678
Cardiovascular System 103 | 15,192

Target Family

Non-IDG 53 | 12,091
Enzyme 36 | 4,145
Kinase 8 | 634
Transcription Factor 7 | 1,400
Epigenetic 3 | 242
Transporter 2 | 473
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
SET domain-containing protein 5 SETD5 Tbio Epigenetic -0.91515 9.39 43
Protein patched homolog 1 PTCH1 Tbio Non-IDG -3.04637 1057.4 452
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -2.06760 110.4 225
V-type proton ATPase 116 kDa subunit a isoform 2 ATP6V0A2 Tbio Enzyme -2.46402 298.9 76
Kinesin-like protein KIF22 KIF22 Tbio Non-IDG -1.69996 54.3 147
Acid ceramidase ASAH1 Tchem Enzyme -2.94716 848.0 203
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 PLOD1 Tbio Enzyme -2.10120 119.8 88
Tyrosine-protein kinase transmembrane receptor ROR2 ROR2 Tbio Kinase -1.88065 80.4 419
Neurogenic locus notch homolog protein 3 NOTCH3 Tchem Non-IDG -2.67185 458.4 499
Inositol polyphosphate 5-phosphatase OCRL-1 OCRL Tbio Enzyme -2.20394 172.2 226