Development Level

Tbio 51 | 10,625
Tchem 45 | 1,890
Tclin 22 | 602
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 5 | 633
abnormal tooth morphology 3 | 24
decreased bone mineral content 3 | 157
increased circulating calcium ... 3 | 32
increased circulating triglyce... 3 | 24
increased hematocrit 3 | 36
increased hemoglobin content 3 | 45
increased mean corpuscular hem... 3 | 93
increased or absent threshold ... 3 | 128
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
decreased caudal vertebrae num... 2 | 49
decreased circulating LDL chol... 2 | 37
decreased circulating alkaline... 2 | 41
decreased circulating chloride... 2 | 32
decreased circulating creatini... 2 | 31
decreased leukocyte cell numbe... 2 | 54
decreased spleen weight 2 | 13
decreased threshold for audito... 2 | 32
embryonic lethality prior to t... 2 | 187
enlarged epididymis 2 | 27
increased circulating HDL chol... 2 | 63
increased circulating LDL chol... 2 | 15
increased circulating alkaline... 2 | 119
increased circulating choleste... 2 | 53
increased circulating phosphat... 2 | 24
increased circulating potassiu... 2 | 31
increased circulating serum al... 2 | 25
increased circulating total pr... 2 | 20
increased mean corpuscular vol... 2 | 91
increased total body fat amoun... 2 | 57
preweaning lethality, incomple... 2 | 260
thrombocytopenia 2 | 46
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal maxilla morphology 1 | 16
abnormal placement of pupils 1 | 4
abnormal retina morphology 1 | 100
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased fasted circulating g... 1 | 49
decreased lactate dehydrogenas... 1 | 14
decreased lean body mass 1 | 195
decreased rib number 1 | 59
decreased total body fat amoun... 1 | 186
enlarged liver 1 | 3
hypoactivity 1 | 89
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased body length 1 | 20
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 17
increased circulating fructosa... 1 | 11
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
increased mean corpuscular hem... 1 | 25
increased respiratory quotient 1 | 12
irregularly shaped pupil 1 | 7
lethargy 1 | 5
narrow eye opening 1 | 15
short tibia 1 | 82
small seminal vesicle 1 | 6
small testis 1 | 37
tremors 1 | 34

Disease

Hyperglycemia 120 | 120
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 120 | 18,473
Female tissues 120 | 18,647
Nervous System 120 | 18,561
Blood and immune system 119 | 17,995
Endocrine System 119 | 18,512
Skin and soft tissues 119 | 18,115
Liver and Pancreas 118 | 18,136
Urinary Tract 117 | 18,444
Cardiovascular System 114 | 17,958
Male tissues 114 | 17,969
Respiratory system 109 | 17,484

Target Family

Non-IDG 53 | 11,971
Enzyme 24 | 4,146
Transcription Factor 17 | 1,400
Kinase 9 | 634
Transporter 9 | 473
Nuclear Receptor 3 | 48
GPCR 2 | 406
Ion Channel 2 | 341
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Forkhead box protein M1 FOXM1 Tbio Transcription Factor -3.09305 1275.4 345
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.30074 2066.8 474
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.33707 243.8 508
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Mitochondrial brown fat uncoupling protein 1 UCP1 Tbio Non-IDG -3.04555 1148.0 252
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648