Development Level

Tbio 28 | 11,445
Tchem 28 | 1,598
Tclin 27 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal behavior 3 | 298
abnormal coat-hair pigmentatio... 2 | 64
abnormal lens morphology 2 | 81
abnormal skin morphology 2 | 50
cataract 2 | 92
decreased fasted circulating g... 2 | 65
decreased neutrophil cell numb... 2 | 42
decreased vertical activity 2 | 208
hyperactivity 2 | 148
increased circulating alanine ... 2 | 13
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
tremors 2 | 39
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal humerus morphology 1 | 11
abnormal incisor color 1 | 3
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal sleep behavior 1 | 70
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased pulmonary respirator... 1 | 5
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired righting response 1 | 26
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating iron lev... 1 | 30
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased lymphocyte cell numb... 1 | 32
increased startle reflex 1 | 112
pale yolk sac 1 | 25
preweaning lethality, incomple... 1 | 499
shortened QRS complex duration 1 | 1

Disease

Hyperalgesia 83 | 83
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 81 | 18,159
Skin and soft tissues 79 | 17,230
Digestive Tract 78 | 17,369
Male tissues 77 | 17,142
Female tissues 76 | 17,400
Liver and Pancreas 75 | 16,750
Blood and immune system 74 | 16,909
Nervous System 74 | 16,725
Urinary Tract 72 | 16,678
Respiratory system 69 | 16,393
Cardiovascular System 59 | 15,192

Target Family

Non-IDG 36 | 12,091
GPCR 13 | 408
Kinase 12 | 634
Ion Channel 11 | 344
Enzyme 7 | 4,145
Transcription Factor 3 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium channel protein type 10 subunit alpha SCN10A Tclin Ion Channel -3.17690 1469.3 126
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
Sodium channel protein type 11 subunit alpha SCN11A Tclin Ion Channel -2.46568 276.3 60
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
Myelin protein P0 MPZ Tbio Non-IDG -2.55919 360.1 301
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.23035 1641.3 479
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.82317 50.9 620