Development Level

Tbio 64 | 11,178
Tchem 10 | 1,885
Tclin 9 | 612
Tdark 4 | 6,569

IMPC Phenotype

preweaning lethality, complete... 5 | 979
decreased body weight 4 | 161
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased circulating choleste... 3 | 93
prenatal lethality prior to he... 3 | 87
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
decreased circulating total pr... 2 | 49
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
increased total body fat amoun... 2 | 134
male infertility 2 | 123
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal forebrain development 1 | 20
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placement of pupils 1 | 6
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
absent seminal vesicle 1 | 4
cardiovascular system phenotyp... 1 | 36
decreased cardiac stroke volum... 1 | 6
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased lumbar vertebrae num... 1 | 2
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased bone mineral density 1 | 72
increased circulating free fat... 1 | 20
increased circulating fructosa... 1 | 13
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
limb grasping 1 | 41
long tibia 1 | 25
premature death 1 | 5
prenatal lethality 1 | 28
short tibia 1 | 97
small uterus 1 | 3

Disease

Hydronephrosis 87 | 87
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Digestive Tract 87 | 17,369
Female tissues 87 | 17,400
Skin and soft tissues 87 | 17,230
Endocrine System 86 | 18,159
Male tissues 86 | 17,142
Urinary Tract 86 | 16,678
Blood and immune system 85 | 16,909
Liver and Pancreas 85 | 16,750
Nervous System 84 | 16,725
Respiratory system 84 | 16,393
Cardiovascular System 80 | 15,192

Target Family

Non-IDG 44 | 12,091
Enzyme 21 | 4,145
Transcription Factor 11 | 1,400
Kinase 5 | 634
Ion Channel 3 | 344
Epigenetic 2 | 242
GPCR 1 | 408

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neutrophil gelatinase-associated lipocalin LCN2 Tbio Enzyme -3.35178 2368.1 847
Copper-transporting ATPase 1 ATP7A Tbio Enzyme -3.08069 1155.0 263
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 HCN3 Tclin Ion Channel -1.65805 34.9 216
Plectin PLEC Tbio Non-IDG -2.50749 337.2 130
Chromodomain-helicase-DNA-binding protein 7 CHD7 Tbio Epigenetic -2.91077 788.8 102
7-dehydrocholesterol reductase DHCR7 Tchem Enzyme -2.44252 276.5 109
Polycystic kidney disease and receptor for egg jelly-related protein PKDREJ Tdark Ion Channel -3.42941 2602.1 26
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase PIGL Tbio Enzyme -2.19025 150.5 95
Peroxisomal biogenesis factor 3 PEX3 Tbio Non-IDG -1.79362 72.7 79
Latent-transforming growth factor beta-binding protein 4 LTBP4 Tbio Non-IDG -1.55113 39.1 57