Development Level

Tbio 45 | 11,651
Tchem 16 | 1,388
Tclin 11 | 612
Tdark 4 | 6,593

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
preweaning lethality, complete... 5 | 979
decreased bone mineral content 4 | 151
abnormal behavior 3 | 298
abnormal gait 2 | 69
decreased circulating alkaline... 2 | 46
decreased mean platelet volume 2 | 25
hyperactivity 2 | 148
limb grasping 2 | 41
tremors 2 | 39
abnormal bone structure 1 | 187
abnormal coat- hair morphology 1 | 19
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal rib morphology 1 | 10
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
absent testes 1 | 6
aorta stenosis 1 | 2
decreased basophil cell number 1 | 16
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart rate 1 | 18
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased threshold for audito... 1 | 26
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating aspartat... 1 | 15
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened QRS complex duration 1 | 1
thin ventricular wall 1 | 24

Disease

Huntington's disease 76 | 76
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 75 | 18,159
Nervous System 75 | 16,725
Skin and soft tissues 75 | 17,230
Digestive Tract 73 | 17,369
Female tissues 72 | 17,400
Liver and Pancreas 72 | 16,750
Male tissues 72 | 17,142
Respiratory system 71 | 16,393
Blood and immune system 70 | 16,909
Urinary Tract 70 | 16,678
Cardiovascular System 64 | 15,192

Target Family

Non-IDG 42 | 12,091
Enzyme 13 | 4,145
Transcription Factor 6 | 1,400
GPCR 5 | 408
Epigenetic 3 | 242
Ion Channel 3 | 344
Transporter 2 | 473
Kinase 1 | 634
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endophilin-A3 SH3GL3 Tbio Non-IDG -1.03962 9.87 97
Sequestosome-1 SQSTM1 Tbio Non-IDG -2.78728 635.1 766
Heat shock factor protein 1 HSF1 Tbio Transcription Factor -2.27852 217.0 1246
D(2) dopamine receptor DRD2 Tclin GPCR -3.28700 1882.2 264
Glial fibrillary acidic protein GFAP Tbio Non-IDG -3.50578 2828.7 1992
Protein kinase C and casein kinase substrate in neurons protein 1 PACSIN1 Tbio Enzyme -1.69638 47.7 226
Intraflagellar transport protein 57 homolog IFT57 Tbio Non-IDG -1.31031 23.8 197
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Glutamate receptor ionotropic, NMDA 2A GRIN2A Tclin Ion Channel -3.09828 1158.1 555
Synapse differentiation-inducing gene protein 1-like SYNDIG1L Tdark Non-IDG -0.55764 3.83 6