Development Level

Tbio 145 | 10,625
Tchem 80 | 1,890
Tclin 41 | 602
Tdark 13 | 7,003

IMPC Term

preweaning lethality, complete... 15 | 633
embryonic lethality prior to t... 8 | 187
decreased body weight 6 | 174
preweaning lethality, incomple... 6 | 260
abnormal retina morphology 5 | 100
abnormal behavior 4 | 226
abnormal lens morphology 3 | 73
abnormal testis morphology 3 | 30
cardiovascular system phenotyp... 3 | 35
decreased bone mineral content 3 | 157
decreased circulating choleste... 3 | 85
decreased circulating glucose ... 3 | 121
decreased lean body mass 3 | 195
increased or absent threshold ... 3 | 128
increased total body fat amoun... 3 | 57
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal snout morphology 2 | 18
abnormal tooth morphology 2 | 24
cataract 2 | 26
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating insulin ... 2 | 75
decreased eosinophil cell numb... 2 | 41
embryonic lethality prior to o... 2 | 148
enlarged epididymis 2 | 27
enlarged heart 2 | 111
enlarged lymph nodes 2 | 27
increased bone mineral density 2 | 52
increased circulating HDL chol... 2 | 63
increased circulating alkaline... 2 | 119
increased circulating choleste... 2 | 53
increased circulating triglyce... 2 | 24
increased startle reflex 2 | 38
limb grasping 2 | 35
persistence of hyaloid vascula... 2 | 22
small testis 2 | 37
abnormal QRS complex 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal sensory capabilities/... 1 | 3
abnormal skin morphology 1 | 23
absent vibrissae 1 | 14
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased fasted circulating g... 1 | 49
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased mean platelet volume 1 | 12
decreased monocyte cell number 1 | 28
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
hydrops fetalis 1 | 22
hypoactivity 1 | 89
increased B cell number 1 | 23
increased NK T cell number 1 | 11
increased T cell number 1 | 15
increased blood urea nitrogen ... 1 | 44
increased circulating bilirubi... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased eosinophil cell numb... 1 | 9
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 25
increased mean platelet volume 1 | 19
increased rib number 1 | 41
increased spleen weight 1 | 3
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
polycystic kidney 1 | 9
premature death 1 | 5
prolonged PR interval 1 | 4
short tibia 1 | 82

Disease

Heart disease 279 | 279
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 277 | 18,473
Endocrine System 277 | 18,512
Female tissues 277 | 18,647
Nervous System 277 | 18,561
Urinary Tract 277 | 18,444
Skin and soft tissues 276 | 18,115
Blood and immune system 274 | 17,995
Cardiovascular System 274 | 17,958
Liver and Pancreas 274 | 18,136
Male tissues 274 | 17,969
Respiratory system 270 | 17,484

Target Family

Non-IDG 144 | 11,969
Enzyme 67 | 4,146
Transcription Factor 17 | 1,400
Kinase 14 | 634
Ion Channel 13 | 341
GPCR 8 | 408
Transporter 8 | 473
Nuclear Receptor 5 | 48
Epigenetic 2 | 242
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Bromodomain adjacent to zinc finger domain protein 2B BAZ2B Tchem TF/Epigenetic -2.13444 130.1 74
Zinc finger protein ZFPM2 ZFPM2 Tbio Transcription Factor -1.75745 57.5 78
Tomoregulin-2 TMEFF2 Tbio Non-IDG -1.85867 81.2 150
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.00824 98.4 170
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.46222 253.3 121
Ankyrin-2 ANK2 Tbio Non-IDG -2.04838 107.1 205
S-adenosylmethionine mitochondrial carrier protein SLC25A26 Tbio Transporter -1.45628 32.7 25
Glutaminase liver isoform, mitochondrial GLS2 Tbio Enzyme -3.09840 1215.3 128
Metalloproteinase inhibitor 4 TIMP4 Tbio Enzyme -1.99351 100.3 348
Glyceraldehyde-3-phosphate dehydrogenase GAPDH Tchem Enzyme -3.66772 4499.1 1649