Development Level

Tbio 150 | 11,178
Tchem 74 | 1,885
Tclin 49 | 612
Tdark 15 | 6,569

IMPC Phenotype

preweaning lethality, complete... 17 | 979
preweaning lethality, incomple... 13 | 499
embryonic lethality prior to t... 10 | 278
abnormal behavior 9 | 298
decreased vertical activity 6 | 208
decreased total body fat amoun... 5 | 207
embryonic lethality prior to o... 5 | 239
abnormal behavioral response t... 4 | 66
abnormal embryo size 3 | 220
abnormal retina morphology 3 | 71
abnormal seminal vesicle morph... 3 | 114
abnormal testis morphology 3 | 43
decreased body weight 3 | 161
decreased lymphocyte cell numb... 3 | 83
enlarged heart 3 | 210
hyperactivity 3 | 148
increased neutrophil cell numb... 3 | 46
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased body length 2 | 101
decreased circulating LDL chol... 2 | 38
decreased circulating insulin ... 2 | 76
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased startle reflex 2 | 75
edema 2 | 59
enlarged lymph nodes 2 | 37
increased bone mineral content 2 | 108
increased circulating choleste... 2 | 66
increased circulating triglyce... 2 | 42
increased heart rate 2 | 23
increased heart weight 2 | 62
increased monocyte cell number 2 | 63
increased vertical activity 2 | 24
limb grasping 2 | 41
small superior vagus ganglion 2 | 74
small testis 2 | 58
abnormal epididymis morphology 1 | 42
abnormal heart left ventricle ... 1 | 16
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal retinal blood vessel ... 1 | 26
abnormal sensory capabilities-... 1 | 8
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
abnormal vertebrae morphology 1 | 18
cardiovascular system phenotyp... 1 | 36
decreased blood urea nitrogen ... 1 | 51
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased hemoglobin content 1 | 68
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased eosinophil cell numb... 1 | 11
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
pale yolk sac 1 | 25
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
small spleen 1 | 19
thin ventricular wall 1 | 24

Disease

Heart disease 288 | 288
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 284 | 18,159
Female tissues 278 | 17,400
Digestive Tract 277 | 17,369
Male tissues 277 | 17,142
Skin and soft tissues 276 | 17,230
Liver and Pancreas 275 | 16,750
Urinary Tract 271 | 16,678
Blood and immune system 269 | 16,909
Respiratory system 269 | 16,393
Nervous System 262 | 16,725
Cardiovascular System 249 | 15,192

Target Family

Non-IDG 154 | 12,091
Enzyme 63 | 4,145
Kinase 17 | 634
Ion Channel 16 | 344
Transcription Factor 13 | 1,400
GPCR 9 | 408
Transporter 8 | 473
Nuclear Receptor 5 | 48
Epigenetic 2 | 242
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neutrophil gelatinase-associated lipocalin LCN2 Tbio Enzyme -3.35178 2368.1 847
Ankycorbin RAI14 Tdark Non-IDG -1.33275 19.5 49
Plasminogen-like protein A PLGLA Tdark Non-IDG -3.96245 15129.1 0
Sarcolipin SLN Tbio Non-IDG -2.17996 148.2 53
Heat shock 70 kDa protein 4 HSPA4 Tbio Non-IDG -3.92672 8635.1 432
E3 ubiquitin-protein ligase UBR5 UBR5 Tbio Enzyme -2.78414 604.6 227
Cardiotrophin-1 CTF1 Tbio Non-IDG -2.30700 246.7 333
Beta-2 adrenergic receptor ADRB2 Tclin GPCR -3.22695 1680.9 829
2,4-dienoyl-CoA reductase, mitochondrial DECR1 Tbio Enzyme -4.22091 15887.9 151
Acyl-coenzyme A synthetase ACSM1, mitochondrial ACSM1 Tbio Enzyme -2.32216 206.5 61