Development Level

Tbio 145 | 10,625
Tchem 80 | 1,890
Tclin 41 | 602
Tdark 13 | 7,003

IMPC Term

preweaning lethality, complete... 15 | 633
embryonic lethality prior to t... 8 | 187
decreased body weight 6 | 174
preweaning lethality, incomple... 6 | 260
abnormal retina morphology 5 | 100
abnormal behavior 4 | 226
abnormal lens morphology 3 | 73
abnormal testis morphology 3 | 30
cardiovascular system phenotyp... 3 | 35
decreased bone mineral content 3 | 157
decreased circulating choleste... 3 | 85
decreased circulating glucose ... 3 | 121
decreased lean body mass 3 | 195
increased or absent threshold ... 3 | 128
increased total body fat amoun... 3 | 57
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal snout morphology 2 | 18
abnormal tooth morphology 2 | 24
cataract 2 | 26
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating alanine ... 2 | 53
decreased circulating insulin ... 2 | 75
decreased eosinophil cell numb... 2 | 41
embryonic lethality prior to o... 2 | 148
enlarged epididymis 2 | 27
enlarged heart 2 | 111
enlarged lymph nodes 2 | 27
increased bone mineral density 2 | 52
increased circulating HDL chol... 2 | 63
increased circulating alkaline... 2 | 119
increased circulating choleste... 2 | 53
increased circulating triglyce... 2 | 24
increased startle reflex 2 | 38
limb grasping 2 | 35
persistence of hyaloid vascula... 2 | 22
small testis 2 | 37
abnormal QRS complex 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal femur morphology 1 | 14
abnormal heart left ventricle ... 1 | 20
abnormal heart morphology 1 | 51
abnormal iris morphology 1 | 12
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal retinal vasculature m... 1 | 15
abnormal sensory capabilities/... 1 | 3
abnormal skin morphology 1 | 23
absent vibrissae 1 | 14
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased fasted circulating g... 1 | 49
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased mean platelet volume 1 | 12
decreased monocyte cell number 1 | 28
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
decreased startle reflex 1 | 48
decreased total retina thickne... 1 | 20
decreased vertical activity 1 | 22
hydrops fetalis 1 | 22
hypoactivity 1 | 89
increased B cell number 1 | 23
increased NK T cell number 1 | 11
increased T cell number 1 | 15
increased blood urea nitrogen ... 1 | 44
increased circulating bilirubi... 1 | 16
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased eosinophil cell numb... 1 | 9
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 25
increased mean platelet volume 1 | 19
increased rib number 1 | 41
increased spleen weight 1 | 3
irregularly shaped pupil 1 | 7
narrow eye opening 1 | 15
polycystic kidney 1 | 9
premature death 1 | 5
prolonged PR interval 1 | 4
short tibia 1 | 82

Disease

Heart disease 279 | 279
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 277 | 18,473
Endocrine System 277 | 18,512
Female tissues 277 | 18,647
Nervous System 277 | 18,561
Urinary Tract 277 | 18,444
Skin and soft tissues 276 | 18,115
Blood and immune system 274 | 17,995
Cardiovascular System 274 | 17,958
Liver and Pancreas 274 | 18,136
Male tissues 274 | 17,969
Respiratory system 270 | 17,484

Target Family

Non-IDG 144 | 11,971
Enzyme 67 | 4,146
Transcription Factor 17 | 1,400
Kinase 14 | 634
Ion Channel 13 | 341
GPCR 8 | 406
Transporter 8 | 473
Nuclear Receptor 5 | 48
Epigenetic 2 | 242
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A Tclin Enzyme -3.31593 2169.0 108
Erythropoietin EPO Tbio Non-IDG -3.90053 8755.8 628
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Apolipoprotein A-I APOA1 Tchem Non-IDG -3.60439 3516.7 901
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Protein SCO2 homolog, mitochondrial SCO2 Tbio Non-IDG -2.16453 144.3 98