Development Level

Tbio 75 | 11,445
Tchem 20 | 1,598
Tclin 6 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 4 | 239
decreased lymphocyte cell numb... 3 | 83
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
increased monocyte cell number 3 | 63
increased neutrophil cell numb... 3 | 46
preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
abnormal lung morphology 2 | 26
abnormal seminal vesicle morph... 2 | 114
abnormal spleen morphology 2 | 55
cataract 2 | 92
hydrometra 2 | 53
increased body weight 2 | 25
increased heart rate 2 | 23
increased spleen weight 2 | 10
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal colon morphology 1 | 3
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye anterior chamber ... 1 | 9
abnormal forebrain morphology 1 | 10
abnormal gait 1 | 69
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal retina morphology 1 | 71
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
decreased T cell number 1 | 15
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating insulin ... 1 | 76
decreased circulating lipase l... 1 | 3
decreased circulating serum al... 1 | 82
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
male infertility 1 | 123
short tibia 1 | 97
shortened RR interval 1 | 17
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

HIV Infections 102 | 102
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 100 | 16,909
Liver and Pancreas 100 | 16,750
Digestive Tract 99 | 17,369
Female tissues 99 | 17,400
Male tissues 99 | 17,142
Skin and soft tissues 99 | 17,230
Endocrine System 98 | 18,159
Respiratory system 98 | 16,393
Urinary Tract 98 | 16,678
Cardiovascular System 96 | 15,192
Nervous System 96 | 16,725

Target Family

Non-IDG 67 | 12,091
Enzyme 22 | 4,145
GPCR 4 | 408
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
Ion Channel 1 | 344
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
C-C motif chemokine 3-like 1 CCL3L1 Tbio Non-IDG -1.80717 51.3 142
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ARAP3 Tbio Non-IDG -0.96067 13.8 85
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
BAG family molecular chaperone regulator 3 BAG3 Tbio Non-IDG -2.26339 208.9 289
Eukaryotic translation initiation factor 3 subunit B EIF3B Tbio Non-IDG -1.83618 70.5 84
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
C-X-C chemokine receptor type 1 CXCR1 Tchem GPCR -2.48051 278.1 378
Sigma non-opioid intracellular receptor 1 SIGMAR1 Tclin Non-IDG -2.28907 210.0 143
Serum albumin ALB Tchem Non-IDG -5.01233 98804.9 2101