Development Level

Tbio 82 | 11,651
Tclin 22 | 612
Tchem 10 | 1,388

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 18 | 979
abnormal behavior 5 | 298
decreased total body fat amoun... 4 | 207
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 4 | 499
decreased circulating choleste... 3 | 93
decreased grip strength 3 | 116
abnormal bone structure 2 | 187
abnormal retinal vasculature m... 2 | 27
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating glucose ... 2 | 126
decreased fasted circulating g... 2 | 65
decreased vertical activity 2 | 208
hyperactivity 2 | 148
hypoactivity 2 | 132
increased erythrocyte cell num... 2 | 39
increased heart weight 2 | 62
prenatal lethality prior to he... 2 | 87
small kidney 2 | 16
abnormal behavioral response t... 1 | 66
abnormal clavicle morphology 1 | 6
abnormal coat- hair morphology 1 | 19
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal pelvic girdle bone mo... 1 | 12
abnormal placement of pupils 1 | 6
abnormal radius morphology 1 | 8
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal rib morphology 1 | 10
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal stomach morphology 1 | 10
abnormal tail movements 1 | 12
abnormal testis morphology 1 | 43
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal urinary bladder morph... 1 | 11
abnormal vertebrae morphology 1 | 18
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
cystolithiasis 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating calcium ... 1 | 36
decreased circulating free fat... 1 | 31
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
enlarged uterus 1 | 11
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased aggression 1 | 4
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
microphthalmia 1 | 26
polycystic kidney 1 | 15
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
small heart 1 | 10
small spleen 1 | 19
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Growth failure 114 | 114
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 111 | 18,159
Blood and immune system 110 | 16,909
Digestive Tract 108 | 17,369
Nervous System 107 | 16,725
Skin and soft tissues 107 | 17,230
Urinary Tract 107 | 16,678
Female tissues 106 | 17,400
Male tissues 105 | 17,142
Liver and Pancreas 103 | 16,750
Respiratory system 101 | 16,393
Cardiovascular System 93 | 15,192

Target Family

Enzyme 50 | 4,145
Non-IDG 39 | 12,091
Transporter 8 | 473
Transcription Factor 7 | 1,400
Kinase 6 | 634
Nuclear Receptor 2 | 48
GPCR 1 | 408
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTP-binding protein SAR1b SAR1B Tbio Enzyme -1.91051 79.7 184
Desmoglein-1 DSG1 Tbio Non-IDG -2.72159 516.2 406
Sialin SLC17A5 Tbio Transporter -2.93541 845.6 63
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 NDUFAF3 Tclin Enzyme -2.16371 139.2 56
F-box/LRR-repeat protein 4 FBXL4 Tbio Non-IDG -1.13805 13.4 82
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial SUCLG1 Tbio Enzyme -2.00981 99.0 78
Paired amphipathic helix protein Sin3a SIN3A Tbio Non-IDG -1.93639 70.1 171
Vasopressin-neurophysin 2-copeptin AVP Tbio Non-IDG -3.92570 8381.2 203
Unconventional myosin-Vb MYO5B Tbio Non-IDG -1.96052 93.4 42
RanBP-type and C3HC4-type zinc finger-containing protein 1 RBCK1 Tbio Non-IDG -1.58319 39.4 224