Development Level

Tbio 178 | 11,445
Tchem 33 | 1,598
Tclin 23 | 613
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 7 | 499
embryonic lethality prior to t... 6 | 278
abnormal behavior 5 | 298
embryonic lethality prior to o... 5 | 239
enlarged heart 5 | 210
hypoactivity 5 | 132
increased fasted circulating g... 5 | 76
decreased grip strength 4 | 116
abnormal behavioral response t... 3 | 66
abnormal bone structure 3 | 187
abnormal sleep behavior 3 | 70
cataract 3 | 92
decreased body weight 3 | 161
decreased circulating amylase ... 3 | 28
decreased circulating glucose ... 3 | 126
decreased circulating triglyce... 3 | 79
decreased mean corpuscular vol... 3 | 79
decreased vertical activity 3 | 208
hyperactivity 3 | 148
increased circulating alkaline... 3 | 122
increased total body fat amoun... 3 | 134
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal femur morphology 2 | 14
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal limb bud morphology 2 | 17
cardiovascular system phenotyp... 2 | 36
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased circulating calcium ... 2 | 36
decreased eosinophil cell numb... 2 | 24
enlarged lymph nodes 2 | 37
increased body length 2 | 32
increased circulating potassiu... 2 | 29
increased heart rate 2 | 23
increased mean corpuscular hem... 2 | 36
increased or absent threshold ... 2 | 101
prenatal lethality prior to he... 2 | 87
abnormal coat- hair morphology 1 | 19
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal joint morphology 1 | 23
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal pericardium morpholog... 1 | 26
abnormal placenta morphology 1 | 5
abnormal pupil morphology 1 | 2
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
anophthalmia 1 | 33
convulsive seizures 1 | 13
corneal opacity 1 | 32
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
edema 1 | 59
enlarged urinary bladder 1 | 8
hemorrhage 1 | 23
hydrometra 1 | 53
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased aggression 1 | 4
increased blood uric acid leve... 1 | 5
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased heart rate variabili... 1 | 7
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
limb grasping 1 | 41
prenatal lethality 1 | 28
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Glaucoma 239 | 239
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 232 | 18,159
Digestive Tract 227 | 17,369
Female tissues 225 | 17,400
Skin and soft tissues 224 | 17,230
Male tissues 223 | 17,142
Nervous System 221 | 16,725
Blood and immune system 217 | 16,909
Urinary Tract 215 | 16,678
Liver and Pancreas 214 | 16,750
Respiratory system 209 | 16,393
Cardiovascular System 193 | 15,192

Target Family

Non-IDG 113 | 12,091
Enzyme 60 | 4,145
Transcription Factor 25 | 1,400
Kinase 18 | 634
Transporter 8 | 473
GPCR 7 | 408
Ion Channel 4 | 344
Epigenetic 3 | 242
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor TNF Tclin Non-IDG -4.71806 50345.6 2958
Vascular endothelial growth factor A VEGFA Tclin Non-IDG -4.27197 19076.6 1809
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607