Development Level

Tbio 57 | 11,651
Tchem 30 | 1,388
Tclin 12 | 612
Tdark 4 | 6,593

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

increased circulating choleste... 7 | 66
preweaning lethality, complete... 7 | 979
increased circulating HDL chol... 6 | 80
preweaning lethality, incomple... 6 | 499
embryonic lethality prior to t... 4 | 278
increased circulating triglyce... 4 | 42
increased lean body mass 4 | 172
increased total body fat amoun... 4 | 134
abnormal embryo size 3 | 220
abnormal gait 3 | 69
decreased body weight 3 | 161
decreased lymphocyte cell numb... 3 | 83
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
increased circulating iron lev... 3 | 30
increased mean corpuscular vol... 3 | 92
limb grasping 3 | 41
abnormal bone mineralization 2 | 38
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
decreased IgG1 level 2 | 8
decreased T cell number 2 | 15
decreased bone mineral density 2 | 126
decreased circulating chloride... 2 | 30
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
increased circulating alanine ... 2 | 13
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating aspartat... 2 | 15
increased circulating bilirubi... 2 | 16
increased circulating phosphat... 2 | 26
increased circulating serum al... 2 | 22
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
small seminal vesicle 2 | 10
thrombocytopenia 2 | 56
vertebral fusion 2 | 23
abnormal brain morphology 1 | 13
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal lymph node morphology 1 | 3
abnormal neural tube morpholog... 1 | 12
abnormal retina morphology 1 | 71
anophthalmia 1 | 33
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased lactate dehydrogenas... 1 | 16
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
enlarged uterus 1 | 11
hydroencephaly 1 | 14
hypoactivity 1 | 132
impaired righting response 1 | 26
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lactate dehydrogenas... 1 | 3
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
pale yolk sac 1 | 25
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
trunk curl 1 | 16

Disease

Fatty liver disease 103 | 103
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 100 | 18,159
Liver and Pancreas 99 | 16,750
Digestive Tract 98 | 17,369
Female tissues 98 | 17,400
Skin and soft tissues 98 | 17,230
Urinary Tract 97 | 16,678
Blood and immune system 96 | 16,909
Male tissues 93 | 17,142
Nervous System 91 | 16,725
Respiratory system 90 | 16,393
Cardiovascular System 87 | 15,192

Target Family

Non-IDG 57 | 12,091
Enzyme 28 | 4,145
Nuclear Receptor 5 | 48
Transcription Factor 5 | 1,400
Kinase 4 | 634
Epigenetic 2 | 242
GPCR 1 | 408
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
Putative uncharacterized protein encoded by MIR7-3HG MIR7-3HG Tdark Non-IDG -0.12740 2.08 0
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Bile acid receptor NR1H4 Tclin Nuclear Receptor -2.57379 350.3 293
EF-hand calcium-binding domain-containing protein 4B CRACR2A Tchem Non-IDG -0.52797 3.72 130
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
Retinoic acid receptor responder protein 2 RARRES2 Tbio Non-IDG -2.41772 314.1 196
Nuclear receptor subfamily 1 group I member 3 NR1I3 Tchem Nuclear Receptor -2.57140 281.2 304
Insulin receptor substrate 2 IRS2 Tbio Non-IDG -2.64133 414.7 227
Resistin RETN Tbio Non-IDG -3.08531 1325.4 684