Development Level

Tbio 55 | 11,445
Tchem 32 | 1,598
Tclin 12 | 613
Tdark 4 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

increased circulating choleste... 7 | 66
preweaning lethality, complete... 7 | 979
increased circulating HDL chol... 6 | 80
preweaning lethality, incomple... 6 | 499
embryonic lethality prior to t... 4 | 278
increased circulating triglyce... 4 | 42
increased lean body mass 4 | 172
increased total body fat amoun... 4 | 134
abnormal embryo size 3 | 220
abnormal gait 3 | 69
decreased body weight 3 | 161
decreased lymphocyte cell numb... 3 | 83
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
increased circulating iron lev... 3 | 30
increased mean corpuscular vol... 3 | 92
limb grasping 3 | 41
abnormal bone mineralization 2 | 38
abnormal heart morphology 2 | 162
abnormal kidney morphology 2 | 65
decreased IgG1 level 2 | 8
decreased T cell number 2 | 15
decreased bone mineral density 2 | 126
decreased circulating chloride... 2 | 30
decreased circulating choleste... 2 | 93
decreased circulating glucose ... 2 | 126
decreased circulating iron lev... 2 | 32
decreased circulating serum al... 2 | 82
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
increased circulating alanine ... 2 | 13
increased circulating alkaline... 2 | 122
increased circulating amylase ... 2 | 25
increased circulating aspartat... 2 | 15
increased circulating bilirubi... 2 | 16
increased circulating phosphat... 2 | 26
increased circulating serum al... 2 | 22
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
small seminal vesicle 2 | 10
thrombocytopenia 2 | 56
vertebral fusion 2 | 23
abnormal brain morphology 1 | 13
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal lymph node morphology 1 | 3
abnormal neural tube morpholog... 1 | 12
abnormal retina morphology 1 | 71
anophthalmia 1 | 33
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating insulin ... 1 | 76
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased lactate dehydrogenas... 1 | 16
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
embryonic growth retardation 1 | 106
enlarged uterus 1 | 11
hydroencephaly 1 | 14
hypoactivity 1 | 132
impaired righting response 1 | 26
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating potassiu... 1 | 29
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased lactate dehydrogenas... 1 | 3
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
pale yolk sac 1 | 25
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
trunk curl 1 | 16

Disease

Fatty liver disease 103 | 103
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 100 | 18,159
Liver and Pancreas 99 | 16,750
Digestive Tract 98 | 17,369
Female tissues 98 | 17,400
Skin and soft tissues 98 | 17,230
Urinary Tract 97 | 16,678
Blood and immune system 96 | 16,909
Male tissues 93 | 17,142
Nervous System 91 | 16,725
Respiratory system 90 | 16,393
Cardiovascular System 87 | 15,192

Target Family

Non-IDG 57 | 12,091
Enzyme 28 | 4,145
Nuclear Receptor 5 | 48
Transcription Factor 5 | 1,400
Kinase 4 | 634
Epigenetic 2 | 242
GPCR 1 | 408
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sorting and assembly machinery component 50 homolog SAMM50 Tbio Non-IDG -2.09079 120.9 124
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Putative glutathione hydrolase 3 proenzyme GGT3P Tdark Enzyme -3.09193 1683.2 0
Fibroblast growth factor 19 FGF19 Tbio Non-IDG -2.54882 334.2 305
Diacylglycerol O-acyltransferase 2 DGAT2 Tchem Enzyme -2.07482 112.0 230
Fatty acid-binding protein, adipocyte FABP4 Tchem Non-IDG -2.73935 617.7 605
Keratin, type I cytoskeletal 18 KRT18 Tbio Non-IDG -3.05211 1057.8 1953
Niemann-Pick C1-like protein 1 NPC1L1 Tclin Non-IDG -2.33312 222.7 139
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Sterol regulatory element-binding protein 2 SREBF2 Tchem Transcription Factor -2.61148 361.0 205